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  1. Article

    Open Access

    Vitiligo-specific soluble biomarkers as early indicators of response to immune checkpoint inhibitors in metastatic melanoma patients

    Immunotherapy with checkpoint inhibitors (CPIs) strongly improved the outcome of metastatic melanoma patients. However, not all the patients respond to treatment and identification of prognostic biomarkers abl...

    Maria Luigia Carbone, Gabriele Madonna, Alessia Capone, Marianna Bove in Scientific Reports (2022)

  2. Article

    Open Access

    Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

    Gut microbiota composition influences the clinical benefit of immune checkpoints in patients with advanced cancer but mechanisms underlying this relationship remain unclear. Molecular mechanism whereby gut mic...

    Clélia Coutzac, Jean-Mehdi Jouniaux, Angelo Paci, Julien Schmidt in Nature Communications (2020)