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    Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma

    Blocking programmed death 1 (PD-1) may enhance the durability of anti-tumor responses that are induced by the combined inhibition of BRAF and MEK1. Here we performed a randomized phase 2 trial ( ...

    Paolo Antonio Ascierto, Pier Francesco Ferrucci, Rosalie Fisher in Nature Medicine (2019)