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  1. Article

    Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes

    We investigated whether random proinsulin levels and proinsulin:C-peptide ratio (PI:C) complement immune and genetic markers for identifying relatives at high risk of type 1 diabetes.

    I. Truyen, P. De Pauw, P. N. Jørgensen, C. Van Schravendijk, O. Ubani… in Diabetologia (2005)

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  2. Article

    Regulation of GAD expression in rat pancreatic islets and brain by γ-vinyl-GABA and glucose

    Glutamic acid decarboxylase (GAD) is an important autoantigen in insulin-dependent diabetes mellitus (IDDM), but little is known about its regulation and function in islet cells. We investigated the effects o...

    J. S. Petersen, K. Rimvall, P. N. Jørgensen, E. Hasselager, A. Moody… in Diabetologia (1998)

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  3. Article

    Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats

    The role of glucagon in diabetic hyperglycaemia has been a matter of controversy because of difficulties in the production of selective glucagon deficiency. We developed a high-capacity (40 nmol/ ml), high-aff...

    C. L. Brand, B. Rolin, P. N. JØrgensen, I. Svendsen, J. S. Kristensen… in Diabetologia (1994)

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