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Article
Open AccessMetabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment
Inhibitors of glycogen breakdown regulate glucose homeostasis by limiting glucose production in diabetes. Here we demonstrate that restrained glycogen breakdown also inhibits cancer cell proliferation and indu...
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Article
Erratum: Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells
Correction to: Gene Therapy (2006) 814–820. doi:10.1038/sj.gt.3302716 Since the publication of the above article, the authors have noticed that the wrong figure has been published for Figure 3e. The correct fi...
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Viral and Mycoplasma pneumoniae community-acquired pneumonia and novel clinical outcome evaluation in ambulatory adult patients in China
Few studies have addressed the etiology and clinical outcomes of community-acquired pneumonia (CAP) treated in an ambulatory setting. We investigated the etiology by the culture of Mycoplasma pneumoniae, urine an...
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Article
Open AccessCadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity
Mitochondria are critical targets in the hepatotoxicity of cadmium (Cd). Abnormal mitochondrial dynamics have been increasingly implicated in mitochondrial dysfunction in pathophysiological conditions. Therefo...
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Article
Open AccessEfficacy and toxicity of external-beam radiation therapy for localised prostate cancer: a network meta-analysis
Many radiation regimens for treating prostate cancer have been used over the years, but which regimen is optimal for localised or locally advanced prostate cancer lacks consensus. We performed a network meta-a...
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Open AccessThe stability of care preferences following acute illness: a mixed methods prospective cohort study of frail older people
Patient preferences are integral to person-centred care, but preference stability is poorly understood in older people, who may experience fluctuant illness trajectories with episodes of acute illness. We aime...
