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  1. No Access

    Article

    Release of cytokines by a fermented lectin-1 (ML-1) free mistletoe extract reflects differences in the reactivity of PBMC in healthy and allergic individuals and tumour patients

    Objective: Mistletoe extracts are used in adjuvant cancer treatment, but little is known concerning their mode of action. There is, however, evidence that antigens in these extracts may stimulate cells of the im...

    G. M. Stein, H. Meink, J. Durst, P. A. Berg in European Journal of Clinical Pharmacology (1996)

  2. No Access

    Article

    Non-lectin component in a fermented extract from Viscum album L. grown on pines induces proliferation of lymphocytes from healthy and allergic individuals in vitro

    Mistletoe preparations have been shown to express immunomodulatory properties. In order to evaluate the stimulatory potency of different mistletoe extracts, peripheral blood mononuclear cells (PBMC) from healt...

    G. Stein, P. A. Berg in European Journal of Clinical Pharmacology (1994)

  3. No Access

    Article

    The inhibitory effects of a positive inotropic quinolinone derivative, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212), on bone-marrow progenitor cells and peripheral lymphocytes

    3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212) is a quinolinone derivative with positive inotropic properties.

    F. W. Busch, A. Tillmann, E. W. Becker… in European Journal of Clinical Pharmacology (1992)

  4. No Access

    Chapter and Conference Paper

    Inhibition of Phytohemagglutinine-Induced T Lymphocyte Proliferation by 6-(octadecyldithio)purine, a Novel Liposomal Prodrug of 6-mercaptopurine

    6-mercaptopurine (6-MP) is used in a variety of immune and neoplastic disorders. The antiproliferative effect on neoplastic and immune competent cells is based on the competitive inhibition of hypoxanthine-gua...

    P. T. Daniel, J. Holzschuh, C. E. Müller… in Biological Monitoring of Exposure and the … (1989)

  5. No Access

    Article

    The pathogenesis of cianidanol-induced fever

    Recently, there has been a variety of reports of adverse drug reactions during therapy with the flavonoid Cianidanol (Ci), a cytoprotective radical scavenger, especially involving haemolytic anaemia and drug f...

    P. T. Daniel, J. Holzschuh, P. A. Berg in European Journal of Clinical Pharmacology (1988)

  6. No Access

    Article

    The specificity of the lymphocyte transformation test in a patient with hypersensitivity reactions to pyrazolone compounds. A 10-week follow-up study before and after rechallenge

    To evaluate the specificity of the lymphocyte transformation test (LTT) in the diagnosis of drug allergy we studied over 71 days an atopic woman with a past history of frequent adverse reactions to pyrazolone ...

    N. W. Brattig, G. -J. Diao, P. A. Berg in European Journal of Clinical Pharmacology (1988)