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Open AccessWidespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly understood, and reported disease effects on the brain vary widely between studies. In an effort to identify commonal...
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Article
Transfusion practices for bone marrow harvests: a survey analysis from the AABB Bone Marrow Quality Improvement Initiative Working Group
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Open AccessOxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia
Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization. Their activity supports critical developmental trajector...
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Article
Blood glucose control using a computer-guided glucose management system in allogeneic hematopoietic cell transplant recipients
Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative treatment for patients with hematological malignancies. However, is associated with substantial rates of morbidity and mortality. W...
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Article
Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice
NMDA glutamate receptors have key roles in brain development, function and dysfunction. Regulatory roles of D-serine in NMDA receptor-mediated synaptic plasticity have been reported. Nonetheless, it is unclear...
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Article
Open AccessAdeno-associated virus serotypes 9 and rh10 mediate strong neuronal transduction of the dog brain
Canine models have many advantages for evaluating therapy of human central nervous system (CNS) diseases. In contrast to nonhuman primate models, naturally occurring canine CNS diseases are common. In contrast...
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Mass Spectral Identification of Vc1.1 and Differential Distribution of Conopeptides in the Venom Duct of Conus victoriae. Effect of Post-Translational Modifications and Disulfide Isomerisation on Bioactivity
Molluscs of the genus Conus (cone shells) are carnivorous, feeding on marine worms, small fish and other marine molluscs. They capture their prey by injecting venom containing hundreds of neurally active peptide ...
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Article
Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases
The purpose was to describe the MRI morphological features and signal intensity (SI) characteristics of 24 histologically proven cases of musculoskeletal soft tissue lymphoma presenting clinically as a suspect...
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Article
Clinical characterization of cardiovascular abnormalities associated with feline mucopolysaccharidosis I and VI
The purpose of this study was to define the cardiovascular abnormalities present in young and adult cats affected with the lysosomal storage diseases mucopolysaccharidosis (MPS) I and MPS VI.
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Article
An unusual presentation of muscular sarcoidosis
Sarcoidosis is a noncaseating granulomatous disease that involves multiple organs, most commonly the lungs, lymph nodes, skin, and eyes, but may be clinically evident in any organ system. Symptomatic muscular ...
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Article
Synovial sarcoma with radiological appearances of primitive neuroectodermal tumour/Ewing sarcoma: differentiation by molecular genetic studies
Synovial sarcoma (SS) arises in soft tissues but may invade adjacent bone. We describe a case of SS presenting as aggressive lysis of the proximal ulna, the imaging of which suggested a primary bone lesion. Ne...
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Evaluation of patellar tracking in symptomatic and asymptomatic individuals by magnetic resonance imaging
To determine the patterns of patellar motion in subjects without knee symptoms using dynamic magnetic resonance imaging (MRI).
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Article
The prevalence and diagnostic significance of fluid-fluid levels in focal lesions of bone
To determine the prevalence and diagnostic significance of fluid-fluid levels (FFLs) in focal bone lesions.
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Recognition and management of patients with high-risk vesicovaginal fistulas: Implications for teaching and research
Vesicovaginal fistulas (VVFs) occurring as a result of obstetric trauma are a vast problem in Nigeria and Ghana, where at least 20 000 women await repair, and fewer than 50 physicians have the necessary expert...
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Article
Short and Long Term Treatment of Essential Hypertension with Felodipine as Monotherapy
The anti-hypertensive efficacy of oral felodipine was assessed in a short term single-blind study and in a long term double-blind study. All patients had essential hypertension (WHO stages I–II) and were aged ...