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  1. No Access

    Article

    Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

    Metastasis occurs frequently after resection of pancreatic cancer (PaC). In this study, we hypothesized that multi-parametric analysis of pre-metastatic liver biopsies would classify patients according to thei...

    Linda Bojmar, Constantinos P. Zambirinis, Jonathan M. Hernandez in Nature Medicine (2024)

  2. Article

    Open Access

    Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

    Pancreatic and colorectal cancers are often KRAS mutated and are incurable when tumor DNA or protein persists or recurs after curative intent therapy. Cancer vaccine ELI-002 2P enhances lymph node delivery and...

    Shubham Pant, Zev A. Wainberg, Colin D. Weekes, Muhammad Furqan in Nature Medicine (2024)

  3. Article

    Open Access

    Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma

    Herein, we investigate the relationship between pancreatic stem cell markers (PCSC markers), CD44, and epithelial-specific antigen (ESA), tumor stroma, and the impact on recurrence outcomes in pancreatic ducta...

    Gokce Askan, Ibrahim Halil. Sahin, Joanne F. Chou, Aslihan Yavas in BMC Cancer (2021)

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    Article

    Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations

    Microsatellite instability, a well-established driver pathway in colorectal carcinogenesis, can develop in both sporadic and hereditary conditions via different molecular alterations in the DNA mismatch repair...

    Tao Wang, Zsofia K. Stadler, Liying Zhang, Martin R. Weiser in Familial Cancer (2018)

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    Reference Work Entry In depth

    Pathologic Classification and Biological Behavior of Pancreatic Neoplasia

    Pancreatic neoplasms are classified according to the normal cells they recapitulate. These neoplasms’ clinicopathologic and biologic characteristics are determined mostly by their cellular lineage. Most are of...

    Olca Basturk, Michelle D. Reid, N. Volkan Adsay in Pancreatic Cancer (2018)

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    Living Reference Work Entry In depth

    Pathologic Classification and Biological Behavior of Pancreatic Neoplasia

    Pancreatic neoplasms are classified according to the normal cells they recapitulate. These neoplasms’ clinicopathologic and biologic characteristics are determined mostly by their cellular lineage. Most are of...

    Olca Basturk, Michelle D. Reid, N. Volkan Adsay in Pancreatic Cancer

  7. No Access

    Reference Work Entry In depth

    Pathologic Classification and Biological Behavior of Pancreatic Neoplasia

    Pancreatic neoplasms are classified according to which normal cell type of this organ they recapitulate, because the clinicopathologic and biologic characteristics of tumors are determined or manifested mostly...

    Olca Basturk, Ipek Coban, N. Volkan Adsay in Pancreatic Cancer (2010)