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Article
3-Substituted Thietane-1,1-Dioxides: Synthesis, Antidepressant Activity, and in Silico Prediction of Their Pharmacokinetic and Toxicological Properties
3-Aryloxy- and 3-phenylsulfanylthietane-1,1-dioxides were synthesized by reacting 3,5-dibromo-1-(1,1-dioxothietan-3-yl)-1,2,4-triazole with sodium phenolates and thiophenolate. The 5-aryloxy- and 5-arenesulfon...
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Article
Reaction of dimethyl (S)-2-(p-tolyl)cyclopropane-1,1-dicarboxylate with acetonitrile
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Article
First synthesis of 2-alkyl- 5-aryl-3,3-bis(methoxycarbonyl)- 4,5-dihydropyrroles
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Article
Synthesis of β-Aminoethyl-substituted Pyrazoles
Methods have been developed for the synthesis of 3,5-dimethyl-4-(2-N-mono- and -disubstituted and also unsubstituted aminoethyl)pyrazoles from 1,1-diacetylcyclopropane.
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Article
Synthesis of New 3,4-Disubstituted Furazans
A series of new 3,4-substituted furazans was synthesized on the basis of the mutual transformations of the functional groups in halogenomethyl and bisacyl derivatives of furazan.
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Article
Electrophilic substitution and electronic structure of indolo[2,3-b]quinoxaline
The nitration and bromination of 6-methylindolo[2,3-b]quinoxaline take place in the 9 position. The reactivity indexes were calculated within the framework of the Hückel MO and CNDO (complete neglect of differ...