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2 Result(s)
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Article
Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I
Type I restriction enzymes bind sequence-specifically to unmodified DNA and subsequently pull the adjacent DNA toward themselves. Cleavage then occurs remotely from the recognition site. The mechanism by which...
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Article
Open AccessRecent insights from in vitro single-molecule studies into nucleosome structure and dynamics
Eukaryotic DNA is tightly packed into a hierarchically ordered structure called chromatin in order to fit into the micron-scaled nucleus. The basic unit of chromatin is the nucleosome, which consists of a shor...
