37 Result(s)
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Article
Hemangioblastomatosis of the central nervous system without von Hippel–Lindau Disease: a case report
We report a very rare case of hemangioblastomatosis in a patient without von Hippel–Lindau disease (VHL). A 50-year-old woman had a history of surgical procedures for total removal of a cerebellar hemangioblas...
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Article
A non-infantile case of desmoplastic infantile astrocytoma
We describe a very rare non-infantile case of desmoplastic infantile astrocytoma (DIA). A 9-year-old boy presented with motor weakness and sensory disturbance in his right upper and lower limbs. CT and MRI sho...
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Article
Prognostic Factors and Therapeutic Problems of Primary Intracranial Choriocarcinoma/Germ-Cell Tumors with High Levels of HCG
Objective: Primary intracranial choriocarcinoma (PICCC)/germ-cell tumors (GCTs) with high levels of human chorionic gonadotropin (HCG) (PICCC/GCTs with HL-HCG) are rare and malignant. The goal of this study was ...
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Article
High 123I-IMP Retention on SPECT Image in Primary Central Nervous System Lymphoma
The purpose of this study is to characterize the time course of N-isopropyl-p-[123I]-iodoamphetamine (123I-IMP) uptake of primary central nervous system lymphomas (PCNSL) comparing with those of other common brai...
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Article
Radiological response and histological changes in malignant astrocytic tumors after stereotactic radiosurgery
Stereotactic radiosurgery is an encouraging approach to deliver higher doses of radiation boost for malignant gliomas safely and precisely. The purpose of this study was to investigate the radiation response a...
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Article
Selection of Eligible Patients with Supratentorial Glioblastoma Multiforme for Gross Total Resection
The purpose of this study is to clarify whether gross total tumor resection can prolong the survival in adult patients with supratentorial glioblastoma multiforme (GBM), and to clarify what subset of these pat...
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Article
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma
Hepatocyte growth factor (HGF) has a stimulatory effect on the synthesis of matrix metalloproteinase-2 (MMP-2), which is involved in glioma invasion. In this study, to clarify the correlation between the expre...
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Article
p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells
The present study was designed to elucidate the relationship between p53 and ceramide, both of which are involved in apoptotic signaling. Treatment of human glioma cells with etoposide caused apoptosis only in...
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Article
Role of Ceramide During Cisplatin-induced Apoptosis in C6 Glioma Cells
Cisplatin is commonly used for the treatment of malignant brain tumors. However, the mechanisms of cell death by cisplatin are not fully understood. Therefore, the present study was designed to elucidate the a...
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Article
Pressure changes observed in Codman-Medos programmable valves following magnetic exposure and filli**
Objects: We wished to find what pressure changes were caused in Codman-Medos programmable valve by magnetic exposure and filli**. This pressure-adjustable valve system was used in an experimental investigation...
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Article
Chordoid meningioma
Chordoid meningioma is a relatively rare variant that is often associated with peritumoral lymphoplasmacellular infiltration causing Castleman syndrome (CS). We present a 44-year-old woman with chordoid mening...
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Article
Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells
Ceramide has recently been regarded as a potential mediator of apoptosis. In the present study, the effects of Bcl-2 and Bax on the ceramide-mediated apoptotic pathways were examined in glioma cells overexpres...
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Article
The Significance of the Expression of Tumor Suppressor Gene DCC in Human Gliomas
Deleted in colorectal carcinoma (DCC) gene has been as a candidate of tumor suppressor genes, has been identified recently and is thought to relate to the metastatic potential in some cancers. We examined the ...
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Article
Clinical trial of external beam-radiotherapy combined with daily administration of low-dose cisplatin for supratentorial glioblastoma multiforme – A pilot study
This trial tested the assumed efficacy and safety of externalbeam-radiotherapy combined with daily administration of low dose cisplatin(CDDP) (ERCLC therapy) for patients with glioblastoma multiforme (GBM).Thi...
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Article
Germinoma in cerebral hemisphere associated with Down syndrome
A Down syndrome patient with germinoma develo** in the cerebral hemisphere is reported. A review of the literature yielded only 14 cases of Down syndrome with brain tumors, including our case. This finding ...
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Article
Messenger RNA fingerprinting analysis using arbitrarily primed PCR (RAP) of genes expressed during rat C6 glioma cell differentiation
To identify differentially expressed genes involved in rat C6 glioma cell differentiation induced by cyclic AMP, we adopted mRNA fingerprinting using arbitrarily primed polymerase chain reaction (PCR) (RAP). F...
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Article
Primary pleomorphic adenoma in posterior cranial fossa
A 35-year-old woman had an intradural tumor in the posterior fossa adjacent to the posterior wall of the left pyramidal bone, which was totally removed and histologically diagnosed as a pleomorphic adenoma. Fo...
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Article
Effectiveness of intraoperative radiation therapy for recurrent supratentorial low grade glioma
Twelve adult patients in the records of 38 patients with histologically verified supratentorial low grade glioma showed recurrence at the Gifu University Hospital between 1980 and 1992. A mean period to recurr...
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Article
Long-term survival in malignant intracranial germ-cell tumors: a report of two cases and a review of the literature
The authors report the successful treatment of two cases of malignant germ-cell tumor. A 12-year-old patient with a pineal immature teratoma and increase of α-fetoprotein serum levels was treated with total ex...
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Article
Identification of placental form of glutathione s-transferase in ACNU-resistant murine glioma cell lines
Expression of the placental form of glutathione S-transferase (GST-P) in 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloro-ethyl)-3-nitrosourea hydrochloride (ACNU)-sensitive 9L and C6 glioma cells, and AC...
