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  1. No Access

    Article

    Modulation of crucial adenosinetriphosphatase activities due to U-74389G administration in a porcine model of intracerebral hemorrhage

    Spontaneous intracerebral hemorrhage (ICH) represents a partially-understood cerebrovascular disease of high incidence, morbidity and mortality. We, herein, report the findings of our study concerning the role...

    Alexios Bimpis, Apostolos Papalois, Stylianos Tsakiris… in Metabolic Brain Disease (2013)

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    Article

    Experimentally-induced Wernicke’s encephalopathy modifies crucial rat brain parameters: the importance of Na+,K+-ATPase and a potentially neuroprotective role for antioxidant supplementation

    Wernicke’s encephalopathy (WE) is a serious neuropsychiatric syndrome caused by chronic alcoholism and thiamine (T) deficiency. Our aim was to shed more light on the pathophysiology of WE, by introducing a mod...

    Apostolos Zarros, Charis Liapi, Hussam Al-Humadi… in Metabolic Brain Disease (2013)

  3. No Access

    Article

    Combined thirty-day exposure to thioacetamide and choline-deprivation alters serum antioxidant status and crucial brain enzyme activities in adult rats

    Choline (Ch) is an essential nutrient that seems to be involved in a wide variety of metabolic reactions and functions that affect the nervous system, while thioacetamide (TAA) is a well-known hepatotoxic agen...

    Charis Liapi, Hussam Al-Humadi, Apostolos Zarros… in Metabolic Brain Disease (2009)

  4. No Access

    Article

    Effects of adult-onset streptozotocin-induced diabetes on the rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase: modulation by L-cysteine

    Uncontrolled diabetes is known to affect the nervous system. The aim of this study was to investigate the effect of the antioxidant L-cysteine (Cys) on the changes caused by adult-onset streptozotocin (STZ)-induc...

    Apostolos Zarros, Charis Liapi, Panagiota Galanopoulou… in Metabolic Brain Disease (2009)

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    Article

    Effects of fulminant hepatic encephalopathy on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase: comparison of the enzymes’ response to in vitro treatment with ammonia

    Hepatic encephalopathy can be a life-threatening complication of fulminant hepatic failure. By understanding the pathophysiology involved in the induction of this neuropsychiatric disorder, future therapeutic ...

    Apostolos Zarros, Stamatios Theocharis, Nikolina Skandali… in Metabolic Brain Disease (2008)