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  1. Article

    Open Access

    Age of onset of obsessive-compulsive disorder differentially affects white matter microstructure

    Previous diffusion MRI studies have reported mixed findings on white matter microstructure alterations in obsessive-compulsive disorder (OCD), likely due to variation in demographic and clinical characteristic...

    Chris Vriend, Niels T. de Joode, Petra J. W. Pouwels, Feng Liu in Molecular Psychiatry (2024)

  2. Article

    Open Access

    The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder

    Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population. Particular thalamic subregions may drive thes...

    Cees J. Weeland, Selina Kasprzak, Niels T. de Joode in Translational Psychiatry (2022)

  3. Article

    Open Access

    Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

    Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2–3% and is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD have been identified, but important knowle...

    Helen Blair Simpson, Odile A. van den Heuvel, Euripedes C. Miguel in BMC Psychiatry (2020)