4 Result(s)
within
Nicholas F. Lahens
Life Sciences
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Article
Open AccessCAMPAREE: a robust and configurable RNA expression simulator
The accurate interpretation of RNA-Seq data presents a moving target as scientists continue to introduce new experimental techniques and analysis algorithms. Simulated datasets are an invaluable tool to accura...
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Article
Open AccessComparative evaluation of full-length isoform quantification from RNA-Seq
Full-length isoform quantification from RNA-Seq is a key goal in transcriptomics analyses and has been an area of active development since the beginning. The fundamental difficulty stems from the fact that RNA...
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Article
Open AccessA comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression
Though Illumina has largely dominated the RNA-Seq field, the simultaneous availability of Ion Torrent has left scientists wondering which platform is most effective for differential gene expression (DGE) analy...
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Article
Open AccessIVT-seq reveals extreme bias in RNA sequencing
RNA-seq is a powerful technique for identifying and quantifying transcription and splicing events, both known and novel. However, given its recent development and the proliferation of library construction meth...
