4 Result(s)
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Nicholas C. Cullen
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessA blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
Blood-based biomarkers for screening may guide tau positrion emissition tomography (PET) scan referrals to optimize prognostic evaluation in Alzheimer’s disease. Plasma Aβ42/Aβ40, pTau181, pTau217, pTau231, Nf...
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Article
Open AccessPlasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations
Plasma biomarkers of amyloid, tau, and neurodegeneration (ATN) need to be characterized in cognitively unimpaired (CU) elderly individuals. We therefore tested if plasma measurements of amyloid-β (Aβ)42/40, ph...
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Article
Open AccessThe ANTsX ecosystem for quantitative biological and medical imaging
The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of multiple open-source software libraries which house top-performing algorithms used worldwide by scientific and research communities for ...
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Article
Open AccessAccelerated inflammatory aging in Alzheimer’s disease and its relation to amyloid, tau, and cognition
It is unclear how pathological aging of the inflammatory system relates to Alzheimer’s disease (AD). We tested whether age-related inflammatory changes in cerebrospinal fluid (CSF) and plasma exist across diff...
