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    Article

    The molecular principles of gene regulation by Polycomb repressive complexes

    Precise control of gene expression is fundamental to cell function and development. Although ultimately gene expression relies on DNA-binding transcription factors to guide the activity of the transcription ma...

    Neil P. Blackledge, Robert J. Klose in Nature Reviews Molecular Cell Biology (2021)

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    Article

    Targeting Polycomb systems to regulate gene expression: modifications to a complex story

    Recent findings have demonstrated that Polycomb repressive complexes (PRCs) control gene expression through their co-recruitment to specific CpG island elements with transcription factors and non-coding RNAs. ...

    Neil P. Blackledge, Nathan R. Rose… in Nature Reviews Molecular Cell Biology (2015)