9 Result(s)
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Nehad M. Alajez
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessAuthor Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
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Article
Open AccessEpigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling
TGFβ signaling plays crucial role during development and cancer, however the role for TGFβ signaling in regulating the noncoding part of the human genome in triple negative breast cancer (TNBC) is still being ...
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Article
Open AccessIntegrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer
Colorectal cancer (CRC) remains a global disease burden and a leading cause of cancer related deaths worldwide. The identification of aberrantly expressed messenger RNA (mRNA), long non-coding RNA (lncRNA), an...
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Article
Open AccessAuthor Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessConcurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo
Despite recent advances in cancer management and therapy, resistance to cytotoxic medications remains a major clinical challenge; hence, combination-based anti-cancer treatment regimens are currently gaining m...
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Article
Open AccessNeoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B
Bone marrow stromal (Mesenchymal) stem cells (MSCs) are multipotent bone cells capable of differentiating into mesoderm-type cells, such as osteoblasts and adipocytes. Existing evidence suggests that transform...
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Open AccessConvergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
Targeting regulatory signaling pathways that control human bone marrow stromal (skeletal or mesenchymal) stem cell (hBMSC) differentiation and lineage fate determination is gaining momentum in the regenerative...
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Article
Open AccessSERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells
TGF-β1, a multifunctional regulator of cell growth and differentiation, is the most abundant bone matrix growth factor. During differentiation of human bone stromal cells (hBMSCs), which constitute bone marrow...
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Article
Open AccessmicroRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection
Breast cancer (BC) is the most common cancer type and the second cause of cancer-related death among women. Therefore, better understanding of breast cancer tumor biology and the identification of novel biomar...
