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  1. Article

    Open Access

    Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium

    The liver hormone hepcidin regulates systemic iron homeostasis. Hepcidin is also expressed by the kidney, but exclusively in distal nephron segments. Several studies suggest hepcidin protects against kidney da...

    Stephanie Probst, Johannes Fels, Bettina Scharner… in Archives of Toxicology (2021)

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  2. No Access

    Article

    Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells

    Cadmium (Cd2+) induces renal proximal tubular (PT) damage, including disruption of the E-cadherin/β-catenin complex of adherens junctions (AJs) and apoptosis. Yet, chronic Cd2+ exposure causes malignant transform...

    Frank Thévenod, Natascha A. Wolff, Ulrich Bork, Wing-Kee Lee… in BioMetals (2007)

  3. No Access

    Article

    Molecular characterization of the renal organic anion transporter 1

    Organic anions of diverse chemical structures are secreted in renal proximal tubules. The first step in secretion, uptake of organic anions across the basolateral membrane of tubule cells, is mediated for the ...

    Gerhard Burckhardt, Natascha A. Wolff, Andrew Bahn in Cell Biochemistry and Biophysics (2002)