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  1. No Access

    Article

    Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells

    Cadmium (Cd2+) induces renal proximal tubular (PT) damage, including disruption of the E-cadherin/β-catenin complex of adherens junctions (AJs) and apoptosis. Yet, chronic Cd2+ exposure causes malignant transform...

    Frank Thévenod, Natascha A. Wolff, Ulrich Bork, Wing-Kee Lee… in BioMetals (2007)

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    Article

    Molecular characterization of the renal organic anion transporter 1

    Organic anions of diverse chemical structures are secreted in renal proximal tubules. The first step in secretion, uptake of organic anions across the basolateral membrane of tubule cells, is mediated for the ...

    Gerhard Burckhardt, Natascha A. Wolff, Andrew Bahn in Cell Biochemistry and Biophysics (2002)

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    Article

    Functional expression of renal organic anion transport in Xenopus laevis oocytes

    Secretion of organic anions by the kidney plays a critical role in the elimination of toxic agents from the body. Recent findings in isolated membranes and intact tissue have demonstrated the participation of ...

    Natascha A. Wolff, Richard M. Philpot… in Molecular and Cellular Biochemistry (1992)

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    Article

    Renal handling of taurine,l-alanine,l-glutamate andd-glucose inOpsanus tau: studies on isolated brush border membrane vesicles

    Renal brush border membrane vesicles (bbmv) from the aglomerular toadfish (Opsanus tau), isolated by differential precipitation, were tested for their ability to actively translocate (i) taurine, known to be secr...

    Natascha A. Wolff, Rolf Kinne, Bernd Elger… in Journal of Comparative Physiology B (1987)