6 Result(s)
within
Naoki Shimojo
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDecreased head circumference at birth associated with maternal tobacco smoke exposure during pregnancy on the Japanese prospective birth cohort study
Maternal tobacco smoke exposure during pregnancy impairs fetal body size, including head circumference (HC) at birth; however, the mechanism still remains unclear. This analysis using a large prospective cohor...
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Article
Open AccessLong-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s
Breastfeeding influences the immune system development in infants and may even affect various immunological responses later in life. Breast milk provides a rich source of early nutrition for infant growth and ...
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Article
Open AccessDUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells
ST2hi memory-type Th2 cells are identified as a pathogenic subpopulation in eosinophilic airway inflammation. These ST2hi pathogenic Th2 cells produce large amount of IL-5 upon T cell receptor stimulation, but no...
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Article
Open AccessThe molecular mechanism for activating IgA production by Pediococcus acidilactici K15 and the clinical impact in a randomized trial
IgA secretion at mucosal sites is important for host defence against pathogens as well as maintaining the symbiosis with microorganisms present in the small intestine that affect IgA production. In the present...
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Article
Open AccessMolecular evolution of the VP1, VP2 and VP3 genes in human rhinovirus species C
Human rhinovirus species C (HRV-C) was recently discovered and this virus has been associated with various acute respiratory illnesses (ARI). However, the molecular evolution of the major antigens of this viru...
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Article
Open AccessPhenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid
Although it is recognized that the abnormal accumulation of amino acid is a cause of the symptoms in metabolic disease such as phenylketonuria (PKU), the relationship between disease severity and serum amino a...
