10 Result(s)
within
Nam-Hyung Kim
Life Sciences
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Article
Open AccessThe role of extracellular vesicles in animal reproduction and diseases
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal physiology and in pathological conditions. EVs can transfer func...
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Article
Open AccessA classical swine fever virus E2 fusion protein produced in plants elicits a neutralizing humoral immune response in mice and pigs
Classical swine fever (CSF) is one of the most important viral diseases of swine worldwide. Although live or attenuated virus vaccines have been used to control CSFV, it is difficult to distinguish vaccinated ...
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Article
Development of Plant-produced E2 Protein for Use as a Green Vaccine Against Classical Swine Fever Virus
Plants are promising host systems for recombinant protein production. However, progress in the commercialization of plant-made proteins (PMPs) has been slow. Only one PMP drug is commercially available. In thi...
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Article
MLL2 is essential for porcine embryo development in vitro
Several germ cell-specific transcription factors essential for ovarian formation and folliculogenesis have been identified and studied. However, their function during early embryo development has been poorly e...
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Article
Zinc depletion activates porcine metaphase II oocytes independently of the protein kinase C pathway
Zinc is an important trace element that regulates several biological functions. This study investigated the role of zinc in the metaphase (M) II arrest of porcine oocytes. N, N, N’, N’-tetrakis(2-pyridylmethyl...
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Article
Production of transgenic spermatozoa by lentiviral transduction and transplantation of porcine spermatogonial stem cells
Spermatogonial stem cells (SSCs) are adult stem cells that transmit genetic information from the parent to the next generation (progeny) in males, and thus, SSCs have used in germline-modification for generati...
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Article
Poly-lysine peptidomimetics having potent antimicrobial activity without hemolytic activity
Diversity of sequence and structure in naturally occurring antimicrobial peptides (AMPs) limits their intensive structure–activity relationship (SAR) study. In contrast, peptidomimetics have several advantages...
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Article
Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis
Plk4 regulates centriole duplication. Two centrosomal scaffold proteins, Cep192 and Cep152, are shown to interact with Plk4 in a temporally and spatially regulated manner, and structural analyses reveal that t...
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Article
Tetracycline-dependent expression of the human erythropoietin gene in transgenic chickens
A critical problem in the production of transgenic animals is the uncontrolled constitutive expression of the foreign gene, which occasionally results in serious physiological disorders in the transgenic anima...
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Article
Molecular characterization of pig α2,3-Gal-β1,3-GalNAc-α2,6-sialyltransferase (pST6GalNAc IV) gene specific for Neu5Acα2-3Galβ1-3GalNAc trisaccharide structure
Sialic acids of glycoconjugates play crucial roles in various biological processes, such as cell-cell communication and cell-substrate interaction. A sisalyltransferase, ST6GalNAc IV (Neu5Ac-α2,3-Gal-β1,3-GalN...
