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  1. Article

    Open Access

    The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples

    Genetic and non-genetic factors contribute to breast cancer development. An epigenome-based signature capturing these components in easily accessible samples could identify women at risk. Here, we analyse the ...

    James E. Barrett, Chiara Herzog, Allison Jones, Olivia C. Leavy in Nature Communications (2022)

  2. Article

    Open Access

    Stability of person-specific blood-based infrared molecular fingerprints opens up prospects for health monitoring

    Health state transitions are reflected in characteristic changes in the molecular composition of biofluids. Detecting these changes in parallel, across a broad spectrum of molecular species, could contribute t...

    Marinus Huber, Kosmas V. Kepesidis, Liudmila Voronina, Maša Božić in Nature Communications (2021)

  3. Article

    Open Access

    Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

    Although thousands of breast cancer cells disseminate and home to bone marrow until primary surgery, usually less than a handful will succeed in establishing manifest metastases months to years later. To ident...

    Melanie Werner-Klein, Ana Grujovic, Christoph Irlbeck in Nature Communications (2020)