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  1. No Access

    Article

    Calcitonin gene-related peptide augments parasympathetic contraction of rabbit tracheal smooth musclein vitro

    The effect of calcitonin gene-related peptide (CGRP) on parasympathetic contraction of rabbit airway smooth muscle was studied under isometric conditionsin vitro. CGRP (10−7 M) did not contract tracheal smooth mu...

    T. Kanemura, J. Tamaoki, S. Horii, N. Sakai, K. Kobayashi, K. Isono… in Agents and Actions (1990)

  2. No Access

    Article

    Inhibition by transforming growth factor (34-43)-α, a TGF-α antagonist, of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats

    The effect of prolonged administration of transforming growth factor (34-43)-alpha, an antagonist of TGF-alpha, on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and on the label...

    M Tatsuta, H Iishi, M Baba, R Hirasawa, K Iseki, H Yano… in British Journal of Cancer (1998)

  3. Article

    Open Access

    Attenuation by all-trans-retinoic acid of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N ′-nitro-N-nitrosoguanidine in Wistar rats

    The effect of prolonged administration of all-trans-retinoic acid (RA) on sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine, and the labelling and apoptotic indices a...

    M Tatsuta, H Iishi, M Baba, R Hirasawa, H Yano, N Sakai… in British Journal of Cancer (1999)

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  4. No Access

    Article

    In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model

    Although most therapeutic strategies to prevent restenosis are designed to inhibit vascular smooth muscle cell (VSMC) proliferation directly, VSMC proliferation might be indirectly inhibited by re-endotheliali...

    K Hayashi, S Nakamura, R Morishita, A Moriguchi, M Aoki, K Matsumoto… in Gene Therapy (2000)

  5. No Access

    Article

    Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons

    To develop a novel strategy to prevent delayed neuronal death (DND) following transient occlusion of arteries, the gene of hepatocyte growth factor (HGF), a novel neurotrophic factor, was transfected into the ...

    K Hayashi, R Morishita, H Nakagami, S Yoshimura, A Hara, K Matsumoto… in Gene Therapy (2001)

  6. No Access

    Article

    Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element ‘decoy’ of nuclear factor-kB binding site as a novel molecular strategy

    The transcription factor, NFkB, plays a pivotal role in the coordinated transactivation of cytokine and adhesion molecule genes involved in atherosclerosis and lesion formation after vascular injury. We hypoth...

    S Yoshimura, R Morishita, K Hayashi, K Yamamoto, H Nakagami, Y Kaneda… in Gene Therapy (2001)

  7. No Access

    Article

    Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus

    Daptomycin (DAP) is widely used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. The emergence of DAP non-susceptible MRSA strains during therapy is a major concern in clinical se...

    Y. Iwata, K. Satou, H. Tsuzuku, K. Furuichi… in European Journal of Clinical Microbiology … (2017)