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Article
Open AccessDrug contraindications in comorbid diseases: a protein interactome perspective
Adverse drug reactions (ADRs) are leading causes of death and drug withdrawals and frequently co-occur with comorbidities. However, systematic studies on the effects of drugs on comorbidities are lacking. Drug...
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Article
Open AccessAuthor Correction: Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
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Article
Open AccessParkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
Genome-wide association studies suggest significant overlaps in Parkinson’s disease (PD) and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. The protein-protein interaction network (‘in...
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Article
Weighted fractional generalized cumulative past entropy and its properties
In this paper, we introduce weighted fractional generalized cumulative past entropy of a nonnegative absolutely continuous random variable. Various properties of the proposed weighted fractional measure are st...
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Article
XAI for intrusion detection system: comparing explanations based on global and local scope
Intrusion Detection System is a device or software in the field of cybersecurity that has become an essential tool in computer networks to provide a secured network environment. Machine Learning based IDS offe...
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Article
On Compatibility/Incompatibility of Two Discrete Probability Distributions in the Presence of Incomplete Specification
Conditional specification of distributions is a develo** area with several applications. In the finite discrete case, a variety of compatible conditions can be derived. In this paper, we revisit a rank–based...
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Article
Fuzzy fault tree reliability analysis based on improved T-S model with application to NC turret
In Takagi and Sugeno (T-S) fuzzy fault tree analysis (FFTA), the construction of T-S fuzzy gates relies too much on expert experience, which will result in inevitable subjective errors. In order to overcome th...
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Chapter and Conference Paper
Prediction of Wake Structure Transition for a Linear Plug Nozzle Using Detached Eddy Simulation (DES)
The base flow of a truncated plug nozzle exhibits a phenomenon called Wake Structure Transition (WST), where in an open base wake develops into a closed wake as the pressure ratio is increased. From design poi...
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Chapter and Conference Paper
Likelihood Ratios in Forensics: What They Are and What They Are Not
The 2009 National Research Council report “Strengthening Forensic Science in the United States: A Path Forward” calls for the quantification of forensic evidence. The likelihood ratio provides one qualitative ...
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Article
Preface to a Special Issue in Memory of Professor Theophilos Cacoullos
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Article
Stochastic Comparisons of General Proportional Mean Past Lifetime Frailty Model
In this paper, the general proportional mean past lifetime frailty model is considered, from which the unconditional cumulative distribution and density functions of the lifetime variable are derived. Dependen...
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Article
Non-Parametric Inference for Gini Covariance and its Variants
We obtain simple non-parametric estimators of Gini-based covariance, correlation and regression coefficients. We then establish the consistency and asymptotic normality of the proposed estimators. We provide a...
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Article
Matrix Variate Distribution Theory under Elliptical Models—V: The Non-Central Wishart and Inverted Wishart Distributions
The non-central Wishart and inverted Wishart distributions are studied in this work under elliptical models; some distributional results are based on some generalizations of the well-known Kummer relations, wh...
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Article
Efficient likelihood-based inference for the generalized Pareto distribution
It is well known that inference for the generalized Pareto distribution (GPD) is a difficult problem since the GPD violates the classical regularity conditions in the maximum likelihood method. For parameter e...
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Article
Malware detection and classification using community detection and social network analysis
Despite the efforts of antivirus vendors and researchers to overcome the threat of malware and its growth, malware remains a rampant problem causing significant economic and intellectual property loss. Malware...
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Article
A robust Birnbaum–Saunders regression model based on asymmetric heavy-tailed distributions
Skew-normal/independent distributions provide an attractive class of asymmetric heavy-tailed distributions to the usual symmetric normal distribution. We use this class of distributions here to derive a robust...
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Article
Open AccessGeneralized and social anxiety disorder interactomes show distinctive overlaps with striosome and matrix interactomes
Mechanisms underlying anxiety disorders remain elusive despite the discovery of several associated genes. We constructed the protein–protein interaction networks (interactomes) of six anxiety disorders and not...
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Article
Orderings of the Smallest Claim Amounts from Exponentiated Location-Scale Models
In actuarial science, it is often of interest to compare stochastically extreme claim amounts from heterogeneous portfolios. In this regard, in the present work, we compare the smallest order statistics arisin...
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Article
On a Family of Discrete Log-Symmetric Distributions
The use of continuous probability distributions has been widespread in problems with purely discrete nature. In general, such distributions are not appropriate in this scenario. In this paper, we introduce a c...
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Chapter and Conference Paper
Turbulent Flow Computations on a Hybrid Unstructured Point Distribution Using Meshless Solver LSFD-U
Upwind—Least Square Finite Difference (LSFD-U) is a generalized finite difference method capable of operating on an arbitrary distribution of points. The method is known to work well on an isotropic distributi...
