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  1. Article

    Open Access

    Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence

    Endothelial cell senescence is the state of permanent cell cycle arrest and plays a critical role in the pathogenesis of age-related diseases. However, a comprehensive understanding of the gene regulatory netw...

    Momoko Ohori, Yusuke Nakayama, Mari Ogasawara-Shimizu, Hiroyoshi Toyoshiba in BMC Genomics (2021)