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  1. Article

    Open Access

    Rv2231c, a unique histidinol phosphate aminotransferase from Mycobacterium tuberculosis, supports virulence by inhibiting host-directed defense

    Nitrogen metabolism of M. tuberculosis is critical for its survival in infected host cells. M. tuberculosis has evolved sophisticated strategies to switch between de novo synthesis and uptake of various amino aci...

    Sheeba Zarin, Mohd. Shariq, Nilisha Rastogi… in Cellular and Molecular Life Sciences (2024)

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  2. No Access

    Chapter

    Emerging Transcriptomic Approaches to Decipher Mycobacterial Complexities

    The word “transcriptome” generally refers to overall RNA species transcribed from DNA (or RNA itself) or transcripts that are present in a cell. The transcriptome includes messenger RNA (mRNA), ribosomal RNA (...

    Jasmine Samal, Nilofer Naqvi, Yashika Ahuja… in Integrated Omics Approaches to Infectious … (2021)

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    Chapter

    Exploration of the Mycobacterial Proteome in the Pathogenesis of TB: A Perspective

    Tuberculosis caused by Mycobacterium tuberculosis (M. tb) with a global burden of 10 million cases in 2019 causes morbidity and mortality if not treated. The constant rise in drug-resistant TB has further aggrava...

    Mohd. Shariq, Sheeba Zarin, Nilisha Rastogi… in Integrated Omics Approaches to Infectious … (2021)