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  1. Article

    Open Access

    Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining

    Genome editing of malaria parasites is key to the generation of live attenuated parasites used in experimental vaccination approaches. DNA repair in Plasmodium generally occurs only through homologous recombinati...

    Mirko Singer, Jennifer Marshall, Kirsten Heiss, Gunnar R. Mair… in Genome Biology (2015)

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