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  1. No Access

    Article

    The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation

    Transcription factors bind DNA sequence motif vocabularies in cis-regulatory elements (CREs) to modulate chromatin state and gene expression during cell state transitions. A quantitative understanding of how moti...

    Daniel S. Kim, Viviana I. Risca, David L. Reynolds, James Chappell… in Nature Genetics (2021)

  2. No Access

    Article

    Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation

    Adam Rubin, Brook Barajas, Mayra Furlan-Magaril and colleagues studied dynamic chromatin across the genome of differentiating human skin keratinocytes, identifying both stable and reorganizing classes of trans...

    Adam J Rubin, Brook C Barajas, Mayra Furlan-Magaril… in Nature Genetics (2017)