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Article
Open AccessThe role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis
Permanent joint dysfunction is a devastating complication in patients with septic arthritis. Staphylococcus aureus (S. aureus) lipoproteins (Lpp), the predominant ligands for TLR2, are known to be arthritogenic a...
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Article
Open AccessStaphylococcus aureus induces DNA damage in host cell
Staphylococcus aureus causes serious medical problems in human and animals. Here we show that S. aureus can compromise host genomic integrity as indicated by bacteria-induced histone H2AX phosphorylation, a marke...
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Article
Open AccessLipid moieties on lipoproteins of commensal and non-commensal staphylococci induce differential immune responses
Lipoproteins (Lpp) of Gram-positive bacteria are major players in alerting our immune system. Here, we show that the TLR2 response induced by commensal species Staphylococcus aureus and Staphylococcus epidermidis