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Article
Open AccessIncreased incidence and diverse manifestations of multiple evanescent white dot syndrome during the COVID-19 pandemic
The advent of coronavirus disease 2019 (COVID-19) pandemic has affected the incidence and course of various diseases and numerous studies have investigated ocular involvement associated with COVID-19 and corre...
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Article
Open AccessA multimodal machine learning model for predicting dementia conversion in Alzheimer’s disease
Alzheimer’s disease (AD) accounts for 60–70% of the population with dementia. Mild cognitive impairment (MCI) is a diagnostic entity defined as an intermediate stage between subjective cognitive decline and de...
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Article
Open AccessLong-term air pollution exposure is associated with higher incidence of ST-elevation myocardial infarction and in-hospital cardiogenic shock
Previous studies have reported the association between myocardial infarction (MI) and air pollution (AP). However, limited information is available regarding the long-term effects of AP on the relative inciden...
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Article
Open AccessChanges in peripapillary microvasculature in patients with type 2 diabetes patients: effect of systemic hypertension
To determine the effect of hypertension (HTN) on the peripapillary microvasculature in type 2 diabetes mellitus (T2DM) patients without diabetic retinopathy (DR). The patients were classified into three groups...
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Article
Open AccessVertical asymmetry analysis of the macular microvasculature in epiretinal membrane patients with open-angle glaucoma
To identify the usefulness of vertical asymmetry analysis of the retinal microvasculature in epiretinal membrane (ERM) patients accompanied by open-angle glaucoma (OAG). Subjects were divided into three groups...
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Article
Open AccessA nationwide study on the current treatment status and natural prognosis of hepatocellular carcinoma in elderly
The aim of this study was to identify the treatment status and natural prognosis of hepatocellular carcinoma (HCC) patients aged 65 years or older in Korea. We analyzed 3,492 patients’ data from the liver canc...
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Article
Open AccessA comparison of peripapillary vessel density between subjects with normal-tension glaucoma and primary open-angle glaucoma with similar extents of glaucomatous damage
The purpose of this study was to identify differences in retinal microvasculature impairments between patients with normal-tension glaucoma (NTG) and those with primary open-angle glaucoma (POAG) with similar ...
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Article
Concurrent self-assembly of RGB microLEDs for next-generation displays
MicroLED displays have been in the spotlight as the next-generation displays owing to their various advantages, including long lifetime and high brightness compared with organic light-emitting diode (OLED) dis...
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Article
Open AccessSsu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Brown adipose tissue (BAT) plays a pivotal role in maintaining body temperature and energy homeostasis. BAT dysfunction is associated with impaired metabolic health. Here, we show that Ssu72 phosphatase is ess...
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Article
Open AccessImpact of high myopia on inner retinal layer thickness in type 2 diabetes patients
To investigate the impact of the combination of type 2 diabetes (DM) and high myopia on inner retinal layer thickness of the macular area. The patients were divided into four groups: control (group 1), patient...
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Article
Open AccessDifferent characteristics of retinal damage between chronic hypertension and hypertensive retinopathy
The purpose of this study was to identify how chronic hypertension (HTN) and hypertensive retinopathy (HTNR) have different effects on retinal damage including inner retinal thinning and microvasculature impai...
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Article
Open AccessEffect of Weiss ring on peripapillary retinal nerve fiber layer thickness measurements using SD-OCT
Spectral-domain optical coherence tomography (SD-OCT) must accurately identify and measure the peripapillary retinal nerve fiber layer (pRNFL) thickness to improve the repeatability and reproducibility, and re...
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Article
Open AccessPeripapillary RNFL/vessel density ratio in patients with type2 diabetes without clinical diabetic retinopathy
To identify how diabetic retinal neurodegeneration (DRN) and microvascular impairment are affected differently by various factors in type 2 diabetes (T2DM) patients without diabetic retinopathy via the ratio o...
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Article
Open AccessComparison of retinal layer thickness and microvasculature changes in patients with diabetic retinopathy treated with intravitreous bevacizumab vs panretinal photocoagulation
To compare changes in retinal layers and microvasculature in diabetic retinopathy (DR) patients after bevacizumab therapy and panretinal photocoagulation (PRP). This prospective study divided patients into two...
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Article
Open AccessLong-term repeatability of peripapillary optical coherence tomography angiography measurements in healthy eyes
This is a prospective observational study to establish the short- and long-term repeatability of measurements of peripapillary optical coherence tomography angiography (OCTA) parameters in healthy eyes and ide...
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Article
Open AccessChanges in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery
To analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain...
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Article
Open AccessEffects of prolonged type 2 diabetes on changes in peripapillary retinal nerve fiber layer thickness in diabetic eyes without clinical diabetic retinopathy
To identify the effects of prolonged type 2 diabetes (T2DM) on changes in peripapillary retinal nerve fiber layer (pRNFL) thickness in patients without clinical diabetic retinopathy. Subjects were divided into...
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Article
Open AccessDevelopment of a species-specific transformation system using the novel endogenous promoter calreticulin from oleaginous microalgae Ettlia sp.
Microalgae not only serve as raw materials for biofuel but also have uses in the food, pharmaceutical, and cosmetic industries. However, regulated gene expression in microalgae has only been achieved in a few ...
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Article
Open AccessDetection of Hepatocellular Carcinoma in Contrast-Enhanced Magnetic Resonance Imaging Using Deep Learning Classifier: A Multi-Center Retrospective Study
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and a leading cause of cancer-related death worldwide. We propose a fully automated deep learning model to detect HCC using hepatobilia...
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Article
Open AccessFlexible endoscopic micro-optical coherence tomography for three-dimensional imaging of the arterial microstructure
Micro-optical coherence tomography (µOCT) is a novel imaging approach enabling visualization of the microstructures of biological tissues at a cellular or sub-cellular level. However, it has been challenging t...