Skip to main content

2 Result(s)

within Min Hak Lee Remove this filter Neurosciences Remove this filter

and

  1. Article

    Open Access

    Bi-directional regulation of AIMP2 and its splice variant on PARP-1-dependent neuronal cell death; Therapeutic implication for Parkinson's disease

    Parthanatos represents a critical molecular aspect of Parkinson's disease, wherein AIMP2 aberrantly activates PARP-1 through direct physical interaction. Although AIMP2 ought to be a therapeutic target for the...

    Min Hak Lee, Ki-Hwan Um, Seok Won Lee, Ye Ji Sun… in Acta Neuropathologica Communications (2024)

    Download PDF (4168 KB) View Article

  2. No Access

    Article

    Anti-apoptotic Splicing Variant of AIMP2 Recover Mutant SOD1-Induced Neuronal Cell Death

    Although a couple of studies have reported that mutant superoxide dismutase 1 (SOD1), one of the causative genes of familial amyotrophic lateral, interacts physically with lysyl-tRNA synthetase (KARS1) by a ga...

    Myung Geun Kook, Mi Ran Byun, Soo Min Lee, Min Hak Lee… in Molecular Neurobiology (2023)