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  1. Article

    Open Access

    Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder

    Sarcopenia, the progressive decline in skeletal muscle mass and function, is observed in various conditions, including cancer and aging. The complex molecular biology of sarcopenia has posed challenges for the...

    Min Hak Lee, Bada Lee, Se Eun Park, Ga Eul Yang in Experimental & Molecular Medicine (2024)

  2. Article

    Open Access

    Brain-targeted delivery of neuroprotective survival gene minimizing hematopoietic cell contamination: implications for Parkinson’s disease treatment

    Neurodegenerative diseases, including Parkinson's disease, Amyotropic Lateral Sclerosis (ALS) and Alzheimer's disease, present significant challenges for therapeutic development due to drug delivery restrictio...

    Min Hak Lee, Sukyeong Kang, Ki-Hwan Um, Seok Won Lee in Journal of Translational Medicine (2024)