28 Result(s)

Article

Apoptosis in the reduced enamel epithelium just after tooth emergence in rats

The reduced enamel epithelium transforms into a stratified squamous epithelium, i.e. a junctional epithelium, as the tooth erupts. In this study, we observed apoptosis in the reduced enamel epithelia of rats j...

Yoshihiro Abiko, Michiko Nishimura, Jiro Arai, Jun Kuraguchi… in Medical Electron Microscopy (1996)

Article

Malignant myoepithelioma of the oral palate: Ultrastructural and immunohistochemical studies and survey of the literature

Malignant myoepithelioma arising in the palatal gland is extremely rare. The present study demonstrated ultrastructural and immunohistochemical features of malignant myoepithelioma transformed from long-standi...

Michiko Nishimura, Yoshihiro Abiko, Tomoyuki Ohuchi… in Medical Electron Microscopy (1998)

Article

Effect of cell plating density and extracellular matrix protein on cell growth of epithelial rests of Malassez in vitro

The present study investigated how cell plating density and extracellular matrix protein influence cell survival of epithelial rests of Malassez (ERM) in vitro. ERM cells were plated on culture dishes coated ...

Michiko Nishimura, Y. Abiko, Jiro Mitamura, Tohru Kaku in Medical Electron Microscopy (1999)

Article

Differential expression of human beta-defensin 2 in keratinized and non-keratinized oral epithelial lesions; immunohistochemistry and in situ hybridization

Human β-defensin(hBD)-2 , an antimicrobial peptide, is produced by various epithelial cells. Because hBD-2 expression in the oral epithelium has not been assessed, we investigated its localization in normal o...

Yoshihiro Abiko, Anura K. Suraweera, Michiko Nishimura, Toshiya Arakawa… in Virchows Archiv (2001)

Article

Expression of inflammatory cytokines and beta-defensin 1 mRNAs in porcine epithelial rests of Malassez in vitro

In the present study, we investigated the mRNA expression of inflammatory cytokines, including interleukin (IL)-1α, IL-6, IL-8, and granulocyte macrophage colony-stimulating factor (GM-CSF), and β defensin 1 ...

Fang Liu, Y. Abiko, Michiko Nishimura, Kaoru Kusano… in Medical Electron Microscopy (2001)

Article

Immunohistochemical localization of amelogenin in human odontogenic tumors, using a polyclonal antibody against bovine amelogenin

In the present study, we investigated the localization of amelogenin in odontogenic tumors, using an anti-amelogenin polyclonal antibody. In order to make the antibody, antisera against an amelogenin fraction...

Y. Abiko, Masaru Murata, Yumi Ito, Toshio Taira… in Medical Electron Microscopy (2001)

Article

Localization of human β-defensin 3 mRNA in normal oral epithelium, leukoplakia, and lichen planus: an in situ hybridization study

 Human β-defensin 3 (hBD-3), an antimicrobial peptide, is produced by various epithelial and some nonepithelial tissues. hBD-3 mRNA is widely expressed in oral tissues, including oral epithelium and the saliva...

Michiko Nishimura, Yoshihiro Abiko, Kaoru Kusano… in Medical Electron Microscopy (2003)

Article

Defensins in saliva and the salivary glands

Saliva contains several types of antimicrobial peptides that play a role in innate immunity. Peptides that were recently added to this list are the defensins. The purpose of this review is to summarize what is...

Yoshihiro Abiko, Michiko Nishimura, Tohru Kaku in Medical Electron Microscopy (2003)

Article

Increased expression of b-defensin-2 and -3 during the development of autoimmune sialoadenitis in MRL/lpr mice

β-Defensins (BD) are small cationic antimicrobial peptides that produced principally in the epithelial cells of a number of organs. The present study analyzed the expression patterns of BD-1, -2, and -3 during...

Masato Saitoh, Yoshihito Kurashige, Mami Yamazaki… in Medical Molecular Morphology (2007)

Article

Role of β-defensins in oral epithelial health and disease

The oral epithelium functions as a mechanical and protective barrier to resist bacterial infection. β-Defensins are a group of antimicrobial peptides mainly produced by epithelial cells of many organs includin...

Yoshihiro Abiko, Masto Saitoh, Michiko Nishimura… in Medical Molecular Morphology (2007)

Article

Expression pattern of p63 in oral epithelial lesions and submucous fibrosis associated with betel-quid chewing in Sri Lanka

Betel-quid chewing, which is closely related to the high incidence of oral cancer, is prevalent in Sri Lanka. p63 has a remarkable structural similarity to p53, suggesting an aberrant expression in oral cancer...

Abusayeed M. Haniffa, Masato Saitoh, Yoshihiro Abiko… in Medical Molecular Morphology (2007)

Article

Expression of claudin-4 and -7 in porcine gingival junctional epithelium

Junctional epithelium, a nonkeratinized stratified epithelium, extends apically in apposition to the surface of the enamel to form a seal between the epithelium and the tooth. Desmosomes and gap junctions adhe...

Masato Saitoh, Yoshito Kurashige, Michiko Nishimura… in Medical Molecular Morphology (2009)

Article

Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line

Human beta-defensins (hBDs), a group of antimicrobial peptides, are involved in the protective barrier of the oral epithelium. Nicotine induces periodontal and oral epithelial diseases. The purpose of the pres...

Sumiko Nakamura, Masato Saitoh, Mami Yamazaki… in Medical Molecular Morphology (2010)

Article

Differentiation of mouse iPS cells into ameloblast-like cells in cultures using medium conditioned by epithelial cell rests of Malassez and gelatin-coated dishes

Induced pluripotent stem (iPS) cells are generated from adult cells and are potentially of great value in regenerative medicine. Recently, it was shown that iPS cells can differentiate into ameloblast-like cel...

Koki Yoshida, Jun Sato, Rie Takai, Osamu Uehara… in Medical Molecular Morphology (2015)

Article

Immunohistochemical evaluation of Klotho and DNA methyltransferase 3a in oral squamous cell carcinomas

Carcinoma follows a course of multiple changes that are affected by several important factors, with epigenetic silencing of the promoter gene being one of them. A series of studies have suggested that epigenet...

Bhoj Raj Adhikari, Osamu Uehara, Hirofumi Matsuoka… in Medical Molecular Morphology (2017)

Article

Effect of systemic administration of lipopolysaccharides derived from Porphyromonas gingivalis on gene expression in mice kidney

Although an association between periodontitis and chronic kidney disease (CKD) has been suggested, the mechanism involved remains unclear. Herein, we examined the global gene expression profile in a mouse mode...

Fumiya Harada, Osamu Uehara, Tetsuro Morikawa… in Medical Molecular Morphology (2018)

Article

Adenomatous ductal proliferation/hyperplasia in the parotid gland associated without any other pathological lesions; a report and survey of the literatures

Adenomatous ductal proliferation/hyperplasia (ADP/H) is a rare hyperplastic condition of the salivary gland. It is mostly associated with other salivary gland pathologies such as tumors and inflammations, and ...

Bhoj Raj Adhikari, Michiko Nishimura, Kosuke Takimoto… in Medical Molecular Morphology (2018)

Article

The Advent of Studies on Jaw Cysts with Keratinization: A Review of Overlooked Papers on Odontogenic Keratocyst and Orthokeratinized Odontogenic Cyst

Previous reports of odontogenic keratocyst (OKC) and orthokeratinized odontogenic cyst (OOC) with coverage of the old literature have tended to overlook the underlying theme of the first description. From a hi...

Fumio Ide, Yumi Ito, Takashi Muramatsu, Yuji Miyazaki… in Head and Neck Pathology (2020)

Article

Ghost/shadow cell differentiation in salivary gland tumors

Fumio Ide, Yumi Ito, Michiko Nishimura, Kentaro Kikuchi, Kaoru Kusama in Virchows Archiv (2020)

Article

So-Called Neuroepithelial Structures in the Posterolateral Tongue: What Can Be Learned from Former Studies?

Fumio Ide, Yumi Ito, Michiko Nishimura, Kaoru Kusama… in Head and Neck Pathology (2020)