26 Result(s)

Article

Soluble CD40 ligand is not solely related to the presence and severity of sepsis

Michelle S Chew, Henrik Thorlacius in Critical Care (2011)

Article

Assessing left ventricular systolic function in shock: evaluation of echocardiographic parameters in intensive care

Assessing left ventricular (LV) systolic function in a rapid and reliable way can be challenging in the critically ill patient. The purpose of this study was to evaluate the feasibility and reliability of, as ...

Lill Bergenzaun, Petri Gudmundsson, Hans Öhlin, Joachim Düring… in Critical Care (2011)

Article

Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock

The diagnosis of acute lung injury (ALI) may be more robust if more accurate physiological markers can be identified. Extravascular lung water (EVLW) is one possible marker, and it has been shown to correlate ...

Michelle S Chew, Lilian Ihrman, Joachim During, Lill Bergenzaun… in Critical Care (2012)

Article

High-sensitive cardiac Troponin T is superior to echocardiography in predicting 1-year mortality in patients with SIRS and shock in intensive care

Left ventricular (LV) dysfunction is well documented in the critically ill. We assessed 1-year mortality in relation to cardiac biomarkers and LV function parameters by echocardiography in patients with shock.

Lill Bergenzaun, Hans Öhlin, Petri Gudmundsson, Joachim Düring… in BMC Anesthesiology (2012)

Article

Depletion of myocardial glucose is observed during endotoxemic but not hemorrhagic shock in a porcine model

Metabolic dysfunction is one of the hallmarks of sepsis yet little is known about local changes in key organs such as the heart. The aim of this study was to compare myocardial metabolic changes by direct meas...

Michelle S Chew, Kiran Shekar, Björn A Brand, Carl Norin, Adrian G Barnett in Critical Care (2013)

Article

Extravascular lung water in acute respiratory distress syndrome and the Berlin definition: time for real change

Michelle S Chew in Critical Care (2013)

Article

Adrenomedullin and endothelin-1 are associated with myocardial injury and death in septic shock patients

Adrenomedullin and endothelin-1 are hormones with opposing effects on the cardiovascular system. Adrenomedullin acts as a vasodilator and seems to be important for the initiation and continuation of the hyperd...

Oscar H. M. Lundberg, Lill Bergenzaun, Jörgen Rydén, Mari Rosenqvist… in Critical Care (2016)

Article

Current use of inotropes in circulatory shock

Treatment decisions on critically ill patients with circulatory shock lack consensus. In an international survey, we aimed to evaluate the indications, current practice, and therapeutic goals of inotrope thera...

Thomas W. L. Scheeren, Jan Bakker, Thomas Kaufmann… in Annals of Intensive Care (2021)

Article

Left ventricular longitudinal wall fractional shortening accurately predicts longitudinal strain in critically ill patients with septic shock

Left ventricular longitudinal strain (LVLS) may be a sensitive indicator of left ventricular (LV) systolic function in patients with sepsis, but is dependent on high image quality and analysis software. Mitral...

Patrik Johansson Blixt, Michelle S. Chew, Rasmus Åhman… in Annals of Intensive Care (2021)

Article

Basic ultrasound head-to-toe skills for intensivists in the general and neuro intensive care unit population: consensus and expert recommendations of the European Society of Intensive Care Medicine 

To provide consensus, and a list of experts’ recommendations regarding the basic skills for head-to-toe ultrasonography in the intensive care setting.

Chiara Robba, Adrian Wong, Daniele Poole, Ashraf Al Tayar… in Intensive Care Medicine (2021)

Article

Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial

We compared dexamethasone 12 versus 6 mg daily for up to 10 days in patients with coronavirus disease 2019 (COVID-19) and severe hypoxaemia in the international, randomised, blinded COVID STEROID 2 trial. In t...

Anders Granholm, Marie Warrer Munch, Sheila Nainan Myatra… in Intensive Care Medicine (2022)

Article

Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia

We assessed long-term outcomes of dexamethasone 12 mg versus 6 mg given daily for up to 10 days in patients with coronavirus disease 2019 (COVID-19) and severe hypoxaemia.

Anders Granholm, Maj-Brit Nørregaard Kjær, Marie Warrer Munch… in Intensive Care Medicine (2022)

Article

Incidence of acute myocardial injury and its association with left and right ventricular systolic dysfunction in critically ill COVID-19 patients

Previous studies have found an increase in cardiac troponins (cTns) and echocardiographic abnormalities in patients with COVID-19 and reported their association with poor clinical outcomes. Whether acute injur...

Saga Jansson, Patrik Johansson Blixt, Helen Didriksson… in Annals of Intensive Care (2022)

Article

Extravascular lung water levels are associated with mortality: a systematic review and meta-analysis

The prognostic value of extravascular lung water (EVLW) measured by transpulmonary thermodilution (TPTD) in critically ill patients is debated. We performed a systematic review and meta-analysis of studies ass...

Francesco Gavelli, Rui Shi, Jean-Louis Teboul, Danila Azzolina… in Critical Care (2022)

Article

Influence of temperature management at 33 °C versus normothermia on survival in patients with vasopressor support after out-of-hospital cardiac arrest: a post hoc analysis of the TTM-2 trial

Targeted temperature management at 33 °C (TTM33) has been employed in effort to mitigate brain injury in unconscious survivors of out-of-hospital cardiac arrest (OHCA). Current guidelines recommend prevention ...

Joachim Düring, Martin Annborn, Alain Cariou, Michelle S. Chew… in Critical Care (2022)

Article

Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial

The optimal ventilatory settings in patients after cardiac arrest and their association with outcome remain unclear. The aim of this study was to describe the ventilatory settings applied in the first 72 h of ...

Chiara Robba, Rafael Badenes, Denise Battaglini, Lorenzo Ball… in Intensive Care Medicine (2022)

Article

Definition and evolution of right ventricular dysfunction in critically ill COVID-19 patients. Author’s reply

Michelle S. Chew, Saga Jansson, Meriam Åström Aneq, Jan Engvall in Annals of Intensive Care (2022)

Article

Effective hemodynamic monitoring

Hemodynamic monitoring is the centerpiece of patient monitoring in acute care settings. Its effectiveness in terms of improved patient outcomes is difficult to quantify. This review focused on effectiveness of...

Michael R. Pinsky, Maurizio Cecconi, Michelle S. Chew, Daniel De Backer… in Critical Care (2022)

Article

How can assessing hemodynamics help to assess volume status?

In critically ill patients, fluid infusion is aimed at increasing cardiac output and tissue perfusion. However, it may contribute to fluid overload which may be harmful. Thus, volume status, risks and potentia...

Daniel De Backer, Nadia Aissaoui, Maurizio Cecconi… in Intensive Care Medicine (2022)

Article

Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO₂) and the episodes of hypoxem...

Chiara Robba, Rafael Badenes, Denise Battaglini, Lorenzo Ball… in Critical Care (2022)