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Modulation of the Immunological Milieu in Acute Aneurysmal Subarachnoid Hemorrhage: The Potential Role of Monocytes Through CXCL10 Secretion

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  1. Article

    Open Access

    Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

    Accumulating evidence suggests that type I interferon (IFN-I) signaling is a key contributor to immune cell-mediated neuropathology in neurodegenerative diseases. Recently, we demonstrated a robust upregulatio...

    Brittany P. Todd, Zili Luo, Noah Gilkes… in Acta Neuropathologica Communications (2023)

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  2. Article

    Open Access

    Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response

    Traumatic brain injury (TBI) is a leading cause of death and disability that lacks neuroprotective therapies. Following a TBI, secondary injury response pathways are activated and contribute to ongoing neurode...

    Brittany P. Todd, Michael S. Chimenti, Zili Luo… in Journal of Neuroinflammation (2021)

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