10 Result(s)
within
Michael Ljungberg
Computational Mathematics and Numerical Analysis
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Article
Open AccessAccuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging.
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Article
Open Access3D printed non-uniform anthropomorphic phantoms for quantitative SPECT
A 3D printing grid-based method was developed to construct anthropomorphic phantoms with non-uniform activity distributions, to be used for evaluation of quantitative SPECT images. The aims were to characteriz...
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Article
Open AccessFeasibility of 177Lu activity quantification using a small portable CZT-based gamma-camera
In image processing for activity quantification, the end goal is to produce a metric that is independent of the measurement geometry. Photon attenuation needs to be accounted for and can be accomplished utiliz...
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Article
Open AccessOn the use of solid 133Ba sources as surrogate for liquid 131I in SPECT/CT calibration: a European multi-centre evaluation
Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed using hollow containers filled with radionuclide solutions. This leads to multiple source...
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Article
Open AccessMonte Carlo modelling of a compact CZT-based gamma camera with application to 177Lu imaging
Semiconductor gamma-camera systems based on cadmium zinc telluride (CZT) detectors present new challenges due to an energy-response that includes effects of low-energy tailing. In particular, such energy tails...
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Article
Open AccessEvaluation of Iodine-123 and Iodine-131 SPECT activity quantification: a Monte Carlo study
The quantitative accuracy of Nuclear Medicine images, acquired for both planar and SPECT studies, is influenced by the isotope-collimator combination as well as image corrections incorporated in the iterative ...
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Article
Open AccessA multicentre and multi-national evaluation of the accuracy of quantitative Lu-177 SPECT/CT imaging performed within the MRTDosimetry project
Patient-specific dosimetry is required to ensure the safety of molecular radiotherapy and to predict response. Dosimetry involves several steps, the first of which is the determination of the activity of the r...
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Article
Open AccessFeasibility of simplifying renal dosimetry in 177Lu peptide receptor radionuclide therapy
Recently, 177Lu-dotatate therapy for neuroendocrine tumours has received regulatory approval. Dosimetry can be used to optimize treatment on an individual basis, but there is no international consensus as to how ...
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Article
Open AccessMonte Carlo-based quantitative pinhole SPECT reconstruction using a ray-tracing back-projector
Monte Carlo simulations provide accurate models of nuclear medicine imaging systems as they can properly account for the full physics of photon transport. The accuracy of the model included in the maximum-like...
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Article
Open AccessEvaluation of inter-departmental variability of ejection fraction and cardiac volumes in myocardial perfusion scintigraphy using simulated data
Myocardial perfusion scintigraphy (MPS) is a clinically useful noninvasive imaging modality for diagnosing patients with suspected coronary artery disease. By utilizing gated MPS, the end diastolic volume (EDV...
