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    Reversal of neurosteroid effects at α4β2δ GABAA receptors triggers anxiety at puberty

    Puberty is characterized by mood swings and anxiety, which are often produced by stress. Here we show that THP (allopregnanolone), a steroid that is released as a result of stress, increases anxiety in puberta...

    Hui Shen, Qi Hua Gong, Chiye Aoki, Maoli Yuan, Yevgeniy Ruderman… in Nature Neuroscience (2007)