5 Result(s)

Article

Nicotinamide Inhibits Self-renewal and Induces Granulocyte Differentiation of Multipotent Progenitor Cells

Nicotinamide (NAM) a form of vitamin B3, is an essential precursor of NAD. This dinucleotide (pyridine nucleotide) participates in the regulation of fundamental processes including transcription, cell cycle pr...

Waseem Nasr, Claire Fabian, Katrin Arnold, Ulrike Köhl… in Stem Cell Reviews and Reports (2020)

Article

Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation

Age-related somatic mutations linked to clonal hematopoiesis have been found in apparently healthy individuals and increase the risk of develo** hematologic malignancies. In acute myeloid leukemia (AML) the ...

Juliane Grimm, Marius Bill, Madlen Jentzsch… in Bone Marrow Transplantation (2019)

Article

Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non-myeloablative conditioning hematopoietic stem cell transplantation

Laura K. Schmalbrock, Lynn Bonifacio, Marius Bill… in Bone Marrow Transplantation (2018)

Chapter

MSCs: Clinical Applications and European Regulatory Aspects

Mesenchymal stromal/stem cells (MSCs) are used to treat a wide variety of diseases. The conditions for which MSCs are administered are often rare and provide an unmet medical need. The biology of MSCs, however...

Jens Reinhardt, Egbert Flory, Isabel Büttel, Christa Schröder… in Mesenchymal Stromal Cells (2013)