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  1. Article

    Open Access

    An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

    We have developed a highly effective method for in vivo gene silencing in the spinal cord and dorsal root ganglia (DRG) by a cationic lipid facilitated delivery of synthetic, small interfering RNA (siRNA). A siRN...

    Miaw-Chyi Luo, Dong-Qin Zhang, Shou-Wu Ma, Yuan-Yuan Huang, Sam J Shuster… in Molecular Pain (2005)

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  2. No Access

    Article

    Dynorphin A activates bradykinin receptors to maintain neuropathic pain

    Dynorphin A is an endogenous opioid peptide that produces non-opioid receptor-mediated neural excitation. Here we demonstrate that dynorphin induces calcium influx via voltage-sensitive calcium channels in sen...

    Josephine Lai, Miaw-Chyi Luo, Qingmin Chen, Shouwu Ma… in Nature Neuroscience (2006)