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Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines

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  1. Article

    Open Access

    Expression and prognostic value of the transcription factors EGR1 and EGR3 in gliomas

    Most glioblastoma patients have a dismal prognosis, although some survive several years. However, only few biomarkers are available to predict the disease course. EGR1 and EGR3 have been linked to glioblastoma...

    Arnon Møldrup Knudsen, Ida Eilertsen, Susanne Kielland… in Scientific Reports (2020)

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  2. Article

    Open Access

    Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation

    Isocitrate dehydrogenase 1 (IDH1) mutations are associated with improved survival in gliomas. Depending on the IDH1 status, TERT promoter mutations affect prognosis. IDH1 mutations are associated with alpha-th...

    Monica Sofia Ventura Ferreira, Mia Dahl Sørensen, Stefan Pusch… in Journal of Neuro-Oncology (2020)

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  3. Article

    Open Access

    Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival

    The mechanisms of glioma-associated seizures (GAS) have yet to be fully elucidated. Proneural subtype, isocitrate dehydrogenase 1 (IDH1) mutations, and epileptic seizures are closely associated suggesting that...

    Christoph Patrick Beier, Tine Rasmussen, Rikke Hedegaard Dahlrot… in Scientific Reports (2018)

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