1,475 Result(s)
within
Mi** Lim
Medicine & Public Health
English
Medicine/Public Health, general
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Article
Open AccessThe effect of four loading intravitreal aflibercept injections on macular fluid in treatment-naïve neovascular age-related macular degeneration
To evaluate the effect of four versus three loading aflibercept injections on macular fluid resolution and visual acuity (VA) in exudative neovascular AMD (nAMD).
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Open AccessHourly step recommendations to achieve daily goals for working and older adults
The widespread use of physical activity trackers enables the collection of high-resolution health data, such as hourly step counts, to evaluate health promotion programmes. We aim to investigate how participan...
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Changes in Illicit Drug Use Among High School Students in Southeastern U.S. States—2009 to 2019
To determine if decreasing lifetime use of methamphetamines, cocaine, ecstasy, and inhalants among high school students occurring from 2009 to 2019 in the U.S. also occurred in five southeastern states, Youth ...
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Open AccessA holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol
Women with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4–6 years after delivery than women without GDM. Similarly, GDM is associated with the devel...
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Open AccessLong-term comparison of renal and metabolic outcomes after sodium–glucose co-transporter 2 inhibitor or glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes
Renal outcomes in patients with type 2 diabetes following treatment with sodium–glucose co-transporter-2 inhibitors (SGLT2is) or glucagon-like peptide-1 receptor agonists (GLP1RAs) have not been directly compa...
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Aficamten reduces symptoms in obstructive hypertrophic cardiomyopathy
Data from the SEQUOIA-HCM trial show that aficamten, a cardiac myosin inhibitor, increases exercise capacity and improves quality of life in patients with symptomatic obstructive hypertrophic cardiomyopathy.
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A phase 1 dose-escalation study of low-dose lenalidomide maintenance post-allogeneic stem cell transplantation for high-risk acute myeloid leukaemia or myelodysplastic syndrome
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Targeting AURKA to induce synthetic lethality in CREBBP-deficient B-cell malignancies via attenuation of MYC expression
Loss-of-function mutations in CREBBP, which encodes for a histone acetyltransferase, occur frequently in B-cell malignancies, highlighting CREBBP deficiency as an attractive therapeutic target. Using established ...
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Exploring the Cognitive Profiles of Haemodialysis Patients using Objective and Subjective Indicators: A Cross-sectional Observational Study
Cognitive impairment is common in haemodialysis patients and associated with adverse health outcomes. Previous work focused primarily on neuropsychological tests, the gold standard measure of cognition. Howeve...
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Open AccessAge-specific association between meal-skip** patterns and the risk of hyperglycemia in Korean adults: a national cross-sectional study using the KNHANES data
Glucose metabolism regulation is influenced by age and meal skip**, although research on their interplay with hyperglycemia remains limited. This study aims to explore the intricate relationship between meal...
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Open AccessUpdate to: Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore
This trial is a parallel, two-arm, non-blinded cluster randomised controlled trial that is under way in Singapore, with the aim of measuring the efficacy of male Wolbachia-infected Aedes aegypti deployments in re...
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Open AccessUse of PSMA PET/CT to detect prostate cancer metastatic to a preexisting thyroid nodule
Prostate cancer (PCa) seldom metastasizes to the thyroid gland, and only a limited number of cases are documented in the literature. The application of a relatively recent and highly sensitive imaging techniqu...
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Higher adiposity predicts greater intra-individual inconsistencies in postprandial glycemic measurements—an analysis of three randomized controlled trials in Asian populations
Acute glycemic responses offer important insights into glucose homeostasis although the repeatability of these measurements particularly in Asian populations remains unclear. This research aimed to critically ...
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RNA interference lowers triglyceride levels
Data from the phase IIb MUIR and ARCHES-2 trials show that RNA interference approaches that target either apolipoprotein C-III or ANGPTL3 significantly reduce plasma triglyceride levels in patients with mixed ...
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Shared and unique transcriptomic signatures of antidepressant and probiotics action in the mammalian brain
Understanding the shared and divergent mechanisms across antidepressant (AD) classes and probiotics is critical for improving treatment for mood disorders. Here we examine the transcriptomic effects of bupropi...
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Open AccessWhole genome sequencing of HER2-positive metastatic extramammary Paget’s disease: a case report
Extramammary Paget’s disease (EMPD) is a rare cancer that occurs within the epithelium of the skin, arising predominantly in areas with high apocrine gland concentration such as the vulva, scrotum, penis and p...
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No benefit of apoA-I infusion after myocardial infarction
In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardial infarction.
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Periodontal treatment reduces AF recurrence
Treatment for periodontal disease might reduce the recurrence of atrial fibrillation (AF) in patients undergoing ablation, suggesting that periodontitis is a modifiable risk factor for AF.
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Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy
According to data from the IMPROVE-HCM trial, ninerafaxstat is well tolerated by patients with symptomatic non-obstructive hypertrophic cardiomyopathy and improves exercise performance among those who are most...
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No benefit of β-blockers after myocardial infarction with preserved ejection fraction
In the REDUCE-AMI trial, the use of β-blockers in patients with acute myocardial infarction (MI) who have undergone early coronary angiography and have a preserved left ventricular ejection fraction did not re...
