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Article
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration
Mutations in the Fused in sarcoma/Translated in liposarcoma gene (FUS/TLS, FUS) have been identified among patients with amyotrophic lateral sclerosis (ALS). FUS protein aggregation is a major pathological hallma...
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Article
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
The TARDBP gene encodes TDP-43, a multifunctional DNA- and RNA-binding protein involved in many cellular processes. Mutations in TARDBP are associated with TDP-43 proteinopathies. In vivo and in vitro studies of ...
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Article
Proinflammatory CD14+CD16+ Monocytes are Associated with Microinflammation in Patients with Type 2 Diabetes Mellitus and Diabetic Nephropathy Uremia
Diabetic nephropathy (DN) is a major cause of type 2 diabetes mellitus (T2DM) mortality. Innate immunity has been shown to be closely associated with the occurrence and progression of T2DM-associated complicat...
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Article
Effects of 1,25-(OH)2D3 on the expressions of vitamin D receptor, STAT5 and cytoskeletal rearrangement in human monocytes incubated with sera from type 2 diabetes patients and diabetic nephropathy patients with uremia
To explore the effects of 1,25-(OH)2D3 and lipopolysaccharide (LPS) plus human recombinant interleukin-15 (IL-15) on expression of vitamin D receptor (VDR) and STAT5, and cytoskeletal rearrangement in human monoc...
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Chapter
Alternative Pre-mRNA Splicing, Cell Death, and Cancer
Alternative splicing is one of the most powerful mechanisms for generating functionally distinct products from a single genetic loci and for fine-tuning gene activities at the post-transcriptional level. Alter...
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Article
Open AccessInternational journal of mental health systems: a bibliometric study
The International Journal of Mental Health Systems (IJMHS) was launched in August 2007 and has recently been given a formal impact factor. This study uses bibliometric indicators to review the performance of t...
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Article
Open AccessImmune privilege of the CNS is not the consequence of limited antigen sampling
Central nervous system (CNS) immune privilege is complex and it is still not understood how CNS antigens are sampled by the peripheral immune system under steady state conditions. To compare antigen sampling f...
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Article
Impact resistance of a novel expanded polystyrene cement-based material
The mechanical property of a novel expanded polystyrene cement-based material (EPS-C), which was prepared by compressing semi-dry materials molding, was investigated. The compressive behavior was analyzed by c...
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Article
Generation of reactive oxygen species during cryopreservation may improve Lilium × siberia pollen viability
During biotic and abiotic stress in plants, reactive oxygen species (ROS) may play two very different roles: high ROS concentrations can exacerbate damage, whereas low concentrations can activate defense respo...
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Article
Au@TiO2 Core–Shell Nanostructures with High Thermal Stability
A catalyst system consisting of core–shell nanostructures with Au core and porous TiO2 shell was synthesized and characterized for room temperature CO oxidation. The core–shell structures were prepared by colloi...
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Article
Open AccessTranscriptomic analysis reveals the roles of microtubule-related genes and transcription factors in fruit length regulation in cucumber (Cucumis sativus L.)
Cucumber (Cucumis sativus L.) fruit is a type of fleshy fruit that is harvested immaturely. Early fruit development directly determines the final fruit length and diameter and consequently the fruit yield and qua...
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Article
LASS2/TMSG1 inhibits growth and invasion of breast cancer cell in vitro through regulation of vacuolar ATPase activity
Homo sapiens longevity assurance homologue 2 of yeast LAG1 (LASS2)/tumor metastasis suppressor gene 1 (TMSG1) was a novel tumor metastasis-related gene identified using messenger RNA differential display from ...
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Chapter and Conference Paper
Local Connectedness Constraint and Contrast Normalization Based Microaneurysm Detection
Diabetic retinopathy is an eye disease that damages the retina and leads to vision loss. As the first sign of diabetic retinopathy, microaneurysm (MA) usually appears as a round small spot, which seems similar...
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Chapter and Conference Paper
Adaptive Multi-Metric Fusion for Person Re-identification
Person re-identification, which aims at recognizing a person of interest across spatially disjoint camera views, is still a challenging task. Plenty of approaches emerge in recent years and some of them achiev...
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Article
Open AccessProceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015
A1 Hope and despair in the current treatment of nasopharyngeal cancer
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Article
Synergetic catalytic effect of α-cyclodextrin on silver nanoparticles loaded in thermosensitive hydrogel
Thermosensitive poly(NIPAAm-co-AMPS) hydrogels were prepared by copolymerization of N-isopropyl acrylamide (NIPAAm) and 2-acrylamido-2-methyl 1-propansulfonic acid (AMPS) by employing N,N′-methylenebis(acrylamide...
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Article
Mechanism of nonylphenol-induced neurotoxicity in F1 rats during sexual maturity
The purpose of this study was to examine whether gestational and lactational exposure to environmental endocrine disrupting chemical, nonylphenol (NP), in pregnant dams would lead to the alterations in hormone...
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Article
Bioassay-guided extraction of crude fucose-containing sulphated polysaccharides from Sargassum fusiforme with response surface methodology
The response surface methodology (RSM) combined with bioassays was employed to optimize the extraction process of crude fucose-containing sulphated polysaccharides (cFCSP) from Sargassum fusiforme. The central co...
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Article
Open AccessSuper-focusing of center-covered engineered microsphere
Engineered microsphere possesses the advantage of strong light manipulation at sub-wavelength scale and emerges as a promising candidate to shrink the focal spot size. Here we demonstrated a center-covered eng...
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Article
Contrasting patterns of sun-red and shade-green leaves of Buxus microphylla in response to gradients of excess light during winter acclimation
Leaf reddening in overwintering evergreens largely restricts their application in landscapes and is generally triggered in response to excess light. To explore how leaves respond to excess light and examine th...
