17 Result(s)
within
Mengxiao **e
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessTransfer learning enables identification of multiple types of RNA modifications using nanopore direct RNA sequencing
Nanopore direct RNA sequencing (DRS) has emerged as a powerful tool for RNA modification identification. However, concurrently detecting multiple types of modifications in a single DRS sample remains a challen...
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Article
Open AccessUltrastrong exciton-plasmon couplings in WS2 multilayers synthesized with a random multi-singular metasurface at room temperature
Van der Waals semiconductors exemplified by two-dimensional transition-metal dichalcogenides have promised next-generation atomically thin optoelectronics. Boosting their interaction with light is vital for pr...
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Article
Open AccessRandomized controlled trial study of intelligent rehabilitation training system for functional ankle instability
To investigate the intervention effect of an intelligent rehabilitation training system on patients with functional ankle instability (FAI) and to advance the research to optimise the effect of FAI rehabilitat...
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Open AccessImaging cellular forces with photonic crystals
Current techniques for visualizing and quantifying cellular forces have limitations in live cell imaging, throughput, and multi-scale analysis, which impede progress in cell force research and its practical ap...
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Open AccessBAIAP2L2 is a novel prognostic biomarker related to migration and invasion of HCC and associated with cuprotosis
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and its pathophysiological mechanisms remain unknown. IRSp53 family members, such as BAIAP2L1, participate in the progressio...
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Open AccessPrediction of cardiovascular disease risk based on major contributing features
The risk of cardiovascular disease (CVD) is a serious health threat to human society worldwide. The use of machine learning methods to predict the risk of CVD is of great relevance to identify high-risk patien...
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Open AccessDddA homolog search and engineering expand sequence compatibility of mitochondrial base editing
Expanding mitochondrial base editing tools with broad sequence compatibility is of high need for both research and therapeutic purposes. In this study, we identify a DddA homolog from Simiaoa sunii (Ddd_Ss) which...
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Open AccessA taxonomy of Chinese hospitals and application to medical dispute resolutions
Medical disputes can be viewed as a negative indicator of health care quality and patient satisfaction. However, dispute prevention from the perspective of systematic supervision is unexplored. This study exam...
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Open AccessSpatially resolved clonal copy number alterations in benign and malignant tissue
Defining the transition from benign to malignant tissue is fundamental to improving early diagnosis of cancer1. Here we use a systematic approach to study spatial genome integrity in situ and describe previously ...
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Open AccessA broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge
The strikingly high transmissibility and antibody evasion of SARS-CoV-2 Omicron variants have posed great challenges to the efficacy of current vaccines and antibody immunotherapy. Here, we screen 34 BNT162b2-...
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Open AccessUntangling the changing impact of non-pharmaceutical interventions and vaccination on European COVID-19 trajectories
Non-pharmaceutical interventions (NPIs) and vaccination are two fundamental approaches for mitigating the coronavirus disease 2019 (COVID-19) pandemic. However, the real-world impact of NPIs versus vaccination...
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Open AccessWho and which regions are at high risk of returning to poverty during the COVID-19 pandemic?
Pandemics such as COVID-19 and their induced lockdowns/travel restrictions have a significant impact on people’s lives, especially for lower-income groups who lack savings and rely heavily on mobility to fulfi...
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Open AccessAnalysis of microbial community structure and volatile compounds in pit mud used for manufacturing Taorong-type Baijiu based on high-throughput sequencing
In this study, the pit mud used in manufacturing Taorong-type Baijiu was collected from the upper, middle, lower and bottom layers of pits at Henan Yangshao Liquor Co., LTD. High-throughput sequencing (HTS) te...
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Open AccessTime- and site-resolved kinetic NMR for real-time monitoring of off-equilibrium reactions by 2D spectrotemporal correlations
Nuclear magnetic resonance (NMR) spectroscopy provides detailed information about dynamic processes through line-shape changes, which are traditionally limited to equilibrium conditions. However, a wealth of i...
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Open AccessSelf-powered multifunctional sensing based on super-elastic fibers by soluble-core thermal drawing
The well-developed preform-to-fiber thermal drawing technique owns the benefit to maintain the cross-section architecture and obtain an individual micro-scale strand of fiber with the extended length up to tho...
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Open AccessDesigner patterned functional fibers via direct imprinting in thermal drawing
Creating micro/nanostructures on fibers is beneficial for extending the application range of fiber-based devices. To achieve this using thermal fiber drawing is particularly important for the mass production o...
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Open AccessExperimental infection of hepatitis E virus induces pancreatic necroptosis in miniature pigs
Infection by hepatitis E virus (HEV) via the oral route causes acute hepatitis. Extra-hepatic manifestations of HEV infection may stem from various causes; however, its distribution in organs such as the liver...
