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  1. Article

    Open Access

    Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia

    Interleukin-7 receptor α (encoded by IL7R) is essential for lymphoid development. Whether acute lymphoblastic leukemia (ALL)-related IL7R gain-of-function mutations can trigger leukemogenesis remains unclear. Her...

    Afonso R. M. Almeida, João L. Neto, Ana Cachucho, Mayara Euzébio… in Nature Communications (2021)

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