7 Result(s)
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Maxim Imakaev
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessAuthor Correction: The 4D Nucleome Data Portal as a resource for searching and visualizing curated nucleomics data
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Open AccessThe 4D Nucleome Data Portal as a resource for searching and visualizing curated nucleomics data
The 4D Nucleome (4DN) Network aims to elucidate the complex structure and organization of chromosomes in the nucleus and the impact of their disruption in disease biology. We present the 4DN Data Portal ( ...
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Article
Open AccessThe genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos
Genome organization involves cis and trans chromosomal interactions, both implicated in gene regulation, development, and disease. Here, we focus on trans interactions in Drosophila, where homologous chromosomes ...
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Publisher Correction: Heterochromatin drives compartmentalization of inverted and conventional nuclei
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Heterochromatin drives compartmentalization of inverted and conventional nuclei
The nucleus of mammalian cells displays a distinct spatial segregation of active euchromatic and inactive heterochromatic regions of the genome1,2. In conventional nuclei, microscopy shows that euchromatin is loc...
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Article
Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Using a single-nucleus Hi-C protocol, the authors find that spatial organization of chromatin during oocyte-to-zygote transition differs between paternal and maternal nuclei within a single-cell zygote.
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Super-resolution imaging reveals distinct chromatin folding for different epigenetic states
Using super-resolution imaging to directly observe the three-dimensional organization of Drosophila chromatin at a scale spanning sizes from individual genes to entire gene regulatory domains, the authors find th...
