8 Result(s)

Article

The genomic landscape of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL, we find that, despite a generally low ...

Samuel W. Brady, Kathryn G. Roberts, Zhaohui Gu, Lei Shi, Stanley Pounds… in Nature Genetics (2022)

Chapter

Modeling OCD Endophenotypes in Zebrafish

Obsessive compulsive disorder (OCD) is a pervasive, debilitating neuropsychiatric disorder. Despite over half a century of effort, OCD has remained remarkably resistant to treatment, partly owing to a lack of ...

Matthew Parker in The rights and wrongs of zebrafish: Behavioral phenoty** of zebrafish (2017)

Article

Exploring genomic alteration in pediatric cancer using ProteinPaint

**n Zhou, Michael N Edmonson, Mark R Wilkinson, Aman Patel, Gang Wu… in Nature Genetics (2016)

Article

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

Anna Andersson, Tanja Gruber, James Downing and colleagues report a genomic analysis of infant acute lymphoblastic leukemias with MLL rearrangements. They identify recurrent activating mutations in tyrosine kinas...

Anna K Andersson, **g Ma, Jianmin Wang, **ang Chen… in Nature Genetics (2015)

Chapter

Particular Aspects of US Patent Law in Biotechnologies

A patent is defined as an exclusive right or rights provided by a government to an inventor for a certain period of time in exchange for the public disclosure of an invention. Patent protection can be sought i...

Scott D. Marty, Derek E. Constantine… in Biopatent Law: European vs. US Patent Law (2014)

Article

The genomic landscape of hypodiploid acute lymphoblastic leukemia

Linda Holmfeldt, Lei Wei et al. report whole-genome and exome sequencing of 40 childhood hypodiploid acute lymphoblastic leukemias.

Linda Holmfeldt, Lei Wei, Ernesto Diaz-Flores, Michael Walsh… in Nature Genetics (2013)