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Article
Noncoding deletions reveal a gene that is critical for intestinal function
Large-scale genome sequencing is poised to provide a substantial increase in the rate of discovery of disease-associated mutations, but the functional interpretation of such mutations remains challenging. Here...
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Article
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
Using a sequence of growth-factor manipulations to mimic embryonic intestinal development in culture, a new study has successfully generated human intestinal tissue in vitro from embryonic and induced pluripotent...