3 Result(s)
within
Matthew Bashton
Human Genetics
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Article
Open AccessSingle-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
Understanding the genetic and nongenetic determinants of tumor protein 53 (TP53)-mutation-driven clonal evolution and subsequent transformation is a crucial step toward the design of rational therapeutic strategi...
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Article
Open AccessDNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease
Chronic hepatitis B infection is characterized by hepatic immune and inflammatory response with considerable variation in the rates of progression to cirrhosis. Genetic variants and environmental cues influenc...
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Article
Open AccessCrowdsourcing genomic analyses of ash and ash dieback – power to the people
Ash dieback is a devastating fungal disease of ash trees that has swept across Europe and recently reached the UK. This emergent pathogen has received little study in the past and its effect threatens to overw...
