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  1. Article

    Open Access

    Mitochondrial A12308G alteration in tRNALeu(CUN) in colorectal cancer samples

    Colorectal cancer is the third most common type of cancer in men and women and the second leading cause of cancer-related deaths in the United States and UK. Colorectal cancer is strongly related to age, with ...

    Fawziah MA Mohammed, Ali Reza Rezaee khorasany, Elaheh Mosaieby… in Diagnostic Pathology (2015)

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    Article

    Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis

    MicroRNA-34 family has anti-proliferative and apoptotic roles. Recent studies have shown that p53 upregulates miR-34 family leading to direct repression of several key oncogenes. Inactivation of miR-34a has be...

    Arash Javeri, Massoud Ghaffarpour, Masoumeh Fakhr Taha… in Medical Oncology (2013)

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    Article

    Coding region analysis of vitamin D receptor gene and its association with active calcium stone disease

    The purpose of this study was to evaluate the impact of vitamin D receptor (VDR) gene polymorphisms on the status of active renal calcium stone formation. Male active renal calcium stone formers (ASF, final N = 1...

    Abbas Basiri, Nasser Shakhssalim, Massoud Houshmand, Amir H. Kashi… in Urological Research (2012)

  4. No Access

    Article

    No mitochondrial DNA deletions but more D-loop point mutations in repeated pregnancy loss

    Repeated pregnancy loss (RPL) occurs in 1 out of 300 couples, and the cause of about 50% of them remains idiopathic. Mitochondria have an important role in human development through ATP production and their in...

    Seyed Mohammad Seyedhassani… in Journal of Assisted Reproduction and Genet… (2010)

  5. No Access

    Article

    Association between trinucleotide CAG repeats of the DNA polymerase gene (POLG) with age of onset of Iranian Friedreich’s ataxia patients

    Friedreich’s ataxia (FRDA), an autosomal recessive neurodegenerative disorder, is in most cases due to a homozygous intronic expansion resulting in the loss of function of frataxin. As mitochondrial DNA (mtDNA...

    Mohammad Mehdi Heidari, Massoud Houshmand, Saman Hosseinkhani… in Neurological Sciences (2008)

  6. No Access

    Article

    Is paternal mitochondrial DNA transferred to the offspring following intracytoplasmic sperm injection?

    During intracytoplasmic sperm injection (ICSI) the whole sperm, including head, midpiece and tail, is injected into the middle area of the oocyte. To find out what happens to the sperm mitochondria after ICSI,...

    Massoud Houshmand, Elisabeth Holme… in Journal of Assisted Reproduction and Genet… (1997)

  7. No Access

    Article

    Atypical presentation of multisystem disorders in two girls with mitochondrial DNA deletions

    We describe two girls with atypical presentations of multisystem disorders due to deletions in mitochondrial DNA (mtDNA). One presented with painful carpopedal spasms due to hypoparathyroidism at the age of 4 ...

    Már H. Tulinius, Anders Oldfors, Elisabeth Holme… in European Journal of Pediatrics (1995)