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  1. No Access

    Article

    Changes in cytochrome P450 enzymes by 1,1-dichloroethylene in rat liver and kidney

    We examined the effect of 1,1-dichloroethylene (1,1-DCE) on microsomal cytochrome P450 (P450) enzymes in rat liver and kidney. Rats were treated intraperitoneally with 1,1-DCE daily for 4 days, at doses of 20...

    Nobumitsu Hanioka, Hideto **no, Tetsuji Nishimura, Masanori Ando in Archives of Toxicology (1997)

  2. No Access

    Article

    Suppression of male-specific cytochrome P450 isoforms by bisphenol A in rat liver

    We examined the effect of bisphenol A (BPA) on microsomal cytochrome P450 (P450) enzymes in rats. Rats were treated intraperitoneally with BPA daily for 4 days, at doses of 10, 20, and 40 mg/kg. Among the P45...

    Nobumitsu Hanioka, Hideto **no, Tetsuji Nishimura, Masanori Ando in Archives of Toxicology (1998)

  3. No Access

    Article

    Effect of 4-tert-octylphenol on cytochrome P450 enzymes in rat liver

    The effects were studied of 4-tert-octylphenol (OP) on hepatic cytochrome P450 enzymes in rats. Rats were treated intraperitoneally with OP twice, at doses of 5, 10, and 20 mg/kg. Among the cytochrome P450-depen...

    Nobumitsu Hanioka, Hideto **no, Youn-Son Chung… in Archives of Toxicology (2000)

  4. No Access

    Article

    Assessment of renal toxicity by analysis of regeneration of tubular epithelium in rats given low-dose cadmium chloride or cadmium-polluted rice for 22 months

    To determine whether low-dose oral administration of cadmium (Cd) induces renal toxicity, six groups of female Sprague-Dawley rats were fed a diet containing low amounts of CdCl2 or Cd-polluted rice at concentra...

    Makotoy Shibutani, Kunitoshi Mitsumori, Naoko Niho… in Archives of Toxicology (2000)