22 Result(s)
within
Masaki Yamaguchi
English
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Article
Open AccessPhase 2 study of ibrutinib plus venetoclax in Japanese patients with relapsed/refractory mantle cell lymphoma
Despite high response rates to initial therapy, most patients with mantle cell lymphoma (MCL) experience relapsed or refractory (R/R) disease. Here, we report the efficacy, safety, and pharmacokinetics of the ...
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Open AccessDirect-micro-fabrication of Hydrophobic Surface with Re-entrant Texture on Metal Produced by Femtosecond-pulsed Laser
Re-entrant textures are promising geometries for hydrophobic surfaces, however a direct processing method of microscale re-entrant textures applicable for general industrial materials such as metals has yet to...
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Open AccessFludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation
Allogeneic hematopoietic cell transplantation (HCT) offers a possible cure for patients with relapsed and refractory non-Hodgkin lymphoma (NHL) through potentially beneficial graft versus lymphoma effects. How...
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Efficacy and safety of Wilms’ tumor 1 helper peptide OCV-501 in elderly patients with acute myeloid leukemia: a multicenter, randomized, double-blind, placebo-controlled phase 2 trial
Complete remission (CR) of acute myeloid leukemia (AML) in elderly patients has a short duration, and there is no suitable post-remission therapy. We explored the role of the Wilms’ tumor 1 helper peptide OCV-...
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Open AccessDirect Laser Processing of Two-Scale Periodic Structures for Superhydrophobic Surfaces Using a Nanosecond Pulsed Laser
Hierarchical structures are promising geometries for superhydrophobic surfaces, however a processing method with a single laser light source that is capable of both one-pass and rapid processing has not been e...
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Open AccessMicrofabrication of re-entrant surface with hydrophobicity/oleophobicity for liquid foods
Re-entrant texturing may potentially improve the hydrophobicity and oleophobicity of a surface. The food industry requires a microfabrication method to keep surfaces clean without leaving a packaging residue f...
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Evaluation of a biosimilar granulocyte colony-stimulating factor for peripheral blood stem cell mobilization in Japanese healthy donors: a prospective study
A “biosimilar” is a biotechnological product with a lower cost profile and equivalent efficacy and safety to the originator, but post-marketing clinical evaluation of biosimilar products has not been adequatel...
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Open AccessSynchronisation of Arabidopsis flowering time and whole-plant senescence in seasonal environments
Synchronisation of flowering phenology has often been observed between individuals within plant species. We expected that a critical role of flowering-time control under natural conditions is a phenological sy...
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Modern Geometric Methods of Distance Determination
Building a 3D picture of the Universe at any distance is one of the major challenges in astronomy, from the nearby Solar System to distant Quasars and galaxies. This goal has forced astronomers to develop tech...
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Fabrication of BIT thick films patterned by proton beam writing
In this study, we fabricated thick films with polyvinylpyrrolidone (PVP) added to bismuth titanate (Bi4Ti3O12) to form a lead-free ferroelectric material. We examined the direct patterning of these materials by u...
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Effect of water velocity on Undaria pinnatifida and Saccharina japonica growth in a novel tank system designed for macroalgae cultivation
Kelps are economically valuable primary producers; therefore, many studies on breeding have attempted to increase kelp productivity and quality. However, most cultivation tests have been performed in the ocean...
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Open AccessRelationship between salivary cortisol and depression in adolescent survivors of a major natural disaster
The purpose of this study was to determine the utility of salivary cortisol levels for screening mental states such as depression in adolescents following a natural disaster. We examined the relationship of sa...
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Open AccessEmpirical voriconazole therapy for febrile neutropenic patients with hematological disorders: a prospective multicenter trial in Japan
An open-label, prospective, multicenter study was conducted between October 2006 and March 2010 to assess the efficacy and safety of intravenous voriconazole (VRCZ) as empirical therapy for antibiotic-refracto...
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Disinfective process of strongly acidic electrolyzed product of sodium chloride solution against Mycobacteria
Electrolyzed acid water (EAW) has been studied for its disinfective potential against pathogenic microbes; however, the bactericidal process against Mycobacteria has not been clearly presented. In this study, to ...
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Late response to low-dose imatinib in patients with chronic phase chronic myeloid leukemia
Imatinib was the first BCR-ABL tyrosine kinase inhibitor to become clinically available. In this study, we retrospectively evaluated the long-term efficacy of low-dose imatinib (final maintenance dose <300 mg ...
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Estimation of restraint stress in rats using salivary amylase activity
The rat is an ideal model animal for studying physical and psychological stresses. Recent human studies have shown that salivary amylase activity is a useful biomarker of stress in our social life. To estimate...
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Patterns of salivary cortisol levels can manifest work stress in emergency care providers
To develop objective assessments of work fatigue, we investigated the patterns of changes in salivary cortisol levels in emergency care providers working extended work shifts. Fourteen subjects, comprising sev...
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Efficacy and safety of micafungin as an empirical therapy for invasive fungal infections in patients with hematologic disorders: a multicenter, prospective study
This study was conducted as a prospective, multicenter trial to evaluate the efficacy and safety of micafungin as an empirical therapy for suspected invasive fungal infections (IFIs), including febrile neutrop...
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Successful Treatment of Refractory Peripheral T-Cell Lymphoma with a Combination of Fludarabine and Cyclophosphamide
We report a case of refractory peripheral T-cell lymphoma (PTCL) successfully treated with a combination of fludarabine and cyclophosphamide (FLU/CY). A 68-year-old man with concurrent PTCL and diffuse large B...
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Flat-Chip Microanalytical Enzyme Sensor for Salivary Amylase Activity
It is considered that measurement of salivary α-amylase activity is a useful tool for evaluating the sympathetic nervous system. The purpose of this research is to demonstrate a new design of a flat-chip micro...
